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ProteomicsProtein kinase C epsilon deletion in AgRP neurons modulates hypothalamic glucose sensing and improves glucose tolerance in mice
Total and phosphoproteomic analysis of liver and white adipose tissue from mice with specific deletion of protein kinase C epsilon in AgRP nerons of the hypothalamus, 30 min after i.p. injection with glucose.
ORGANISM(S): Mus musculus (Mouse) 
2026-02-09 | PXD065137 | Pride
Glucose agrp neuron hypothalamus protein kinase c epsilon 
TranscriptomicsCold induced mouse interscapular brown and inguinal white adipose tissue
Adult mouse were cold induced, RNAseq was performed for interscapular brown and inguinal white adipose tissue
ORGANISM(S): Mus musculus 
2019-08-05 | E-MTAB-7565 | biostudies-arrayexpress
TranscriptomicsThe transient inactivation of the master cell cycle phosphatase Cdc14 causes genomic instability in diploid cells of Saccharomyces cerevisiae.
Genomic instability is a common feature found in cancer cells. Accordingly, many tumor suppressor genes identified in familiar cancer syndromes are involved in the maintenance of the stability of the genome during every cell division, and are commonly referred to as caretakers. Inactivating mutation...
ORGANISM(S): Saccharomyces cerevisiae 
2015-05-05 | E-GEOD-68530 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Hepatitis C patients - responders and non-responders to antiviral therapies peg interferon and ribavirin against hepatitis C
Time series of gene expression arrays before and during treatment of Hepatitis C; days 0, 1, 2, 7, 14 and 28 for 69 participants (IDs 1 through 69 are used). Treating chronic hepatitis C using peginterferon alpha and ribavirin leads to sustained clearance of virus and clinical improvement in approxi...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-7123 | biostudies-arrayexpress
UnknownFunctional MRI study in a case of Charles Bonnet syndrome related to LHON.
Not available
S-EPMC6937628 | biostudies-literature
TranscriptomicsTranscription profiling by array of mouse BALBc strain mesenteric lymph nodes after response to common allergens.
In this study, MLN transcriptome profiling of female BALB/c mice was conducted in order to explore the molecular mechanism(s) of antigen sensitization using three of the most common food allergens; BLG, OVA and PNA. Analysis of cDNA microarray data revealed a complex network of genes that is modulat...
ORGANISM(S): Mus musculus 
2011-05-11 | E-MEXP-2676 | biostudies-arrayexpress
UnknownDe novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific.
Not available
S-EPMC2930432 | biostudies-literature
UnknownA genome-wide association study identifies candidate loci associated to syringomyelia secondary to Chiari-like malformation in Cavalier King Charles Spaniels.
Not available
S-EPMC5865342 | biostudies-literature
ProteomicsTherapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury
Background: Ischemia-reperfusion injury (IRI) is one of the major risk factors implicated in morbidity and mortality associated with cardiovascular disease. During cardiac ischemia, the build-up of acidic metabolites results in decreased intracellular and extracellular pH that can reach as low as 6....
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2022-11-01 | PXD024581 | Pride
Heart Venom Mass spectrometry Therapeutic Human induced pluripotent stem cells Ischemia-reperfusion injury 
TranscriptomicsClariom S Microarray from gWAT RNA of female and male offspring of T3 treated and control dams
This study analysed the effect of maternal hyperthyroidism on the offspring’s white adipose tissue function. Hyperthyroidism during pregnancy was induced in wild type female C57BL/6NCrl (Charles River, Germany) at the age of three to four month with 0.5 mg/L T3 (3,3’,5-Triiodo-L-thyronine, T6397, Si...
ORGANISM(S): Mus musculus 
2024-12-30 | E-MTAB-14515 | biostudies-arrayexpress
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