Sort   by:  
 Page size 
UnknownIncorporating Digital Tools to Improve Clinical Trial Infrastructure: A White Paper From the Digital Engagement Committee of SWOG.
Not available
S-EPMC6668704 | biostudies-literature
MetabolomicsMultiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia

The effects of iron deficiency (ID) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, sensitive biomarkers of iron-dependent brain health are lacking in humans. To determine whether serum and cer...

2022-07-12 | MTBLS3388 | MetaboLights
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
MetabolomicsTowards improving point-of-care diagnosis of non-malaria febrile illness: a metabolomics approach
Background: Non-malaria febrile illnesses such as bacterial bloodstream infections (BSI) are a leading cause of disease and mortality in the tropics. However, there are no reliable, simple diagnostic tests for identifying BSI or other severe non-malaria febrile illnesses. We hypothesized that differ...
2016-03-17 | MTBLS315 | MetaboLights
TranscriptomicsNucleosome Distribution Data for Methylphenidate Treatment
Jurkat T-leukemic cells at 0, 15, 45, and 240 minutes post MPH treatment. Chromatin structure depends highly on the position and density of nucleosomes in the genome. The distribution of these nucleosomes likely plays a critical role in all processes for which DNA is the template, including: gene ex...
ORGANISM(S): Homo sapiens 
2015-06-26 | E-GEOD-70292 | biostudies-arrayexpress
UnknownCognate antigen engagement induces HIV-1 expression in latently infected CD4<sup>+</sup> T cells from people on long-term antiretroviral therapy.
Not available
S-EPMC11896817 | biostudies-literature
TranscriptomicsGenome-Wide Analysis In Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
Techniques for systematically monitoring protein translation have lagged far behind methods for measuring mRNA levels. Here we present a ribosome profiling strategy, based on deep sequencing of ribosome protected mRNA fragments, that enables genome-wide investigation of translation with sub-codon re...
ORGANISM(S): Saccharomyces cerevisiae 
2009-02-12 | E-GEOD-13750 | biostudies-arrayexpress
GenomicsNational Heart, Lung, and Blood Institute (NHLBI) Bench to Bassinet Program: The Pediatric Cardiac Genetics Consortium (PCGC)

Multi-center, prospective observational cohort study of individuals with congenital heart defects (CHD). Phenotypic data and source DNA of probands, parents, and families of interest are being collected to investigate relationships between genetic factors and phenotypic and clinical outcomes in p...

phs000571.v1.p1 | EGA
UnknownProgression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation.
Not available
S-EPMC7953587 | biostudies-literature
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
Sort   by:  
 Page size