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In the present study we sought to identify the naturally processed and presented immunopeptidome of the SARS-CoV-2 spike glycoprotein from human antigen presenting cells. Monocyte-derived dendritic cells from a panel of healthy human subjects representing a majority of the HLA-DRB1 allele usage with...
ORGANISM(S): Sars Coronavirus (ncbitaxon:227859) Bos (ncbitaxon:9903) Homo Sapiens (ncbitaxon:9606) 
2020-05-21 | MSV000085456 | MassIVE
Small interfering RNAs (siRNAs) direct RNA interference (RNAi) in eukaryotes. In flies, somatic cells produce siRNAs from exogenous double-stranded RNA as a defense against viral infection. Here, we identify 21-nt long, endogenous siRNAs (endo-siRNAs) corresponding to transposons and heterochromatic...
ORGANISM(S): Drosophila melanogaster 
The S-glutathionylation and phosphorylation proteomes of mouse hearts were analyzed using shotgun proteomics methods in order to assess the effects of aging and the ability of mitochondrion-targeted drug SS-31 to reverse age-related changes. There was a nearly universal increase in S-gluthationylati...
ORGANISM(S): Mus Musculus 
2022-03-16 | PXD024247 | panorama
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