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ProteomicsEgg White as a quality control in MALDI Mass Spectrometry Imaging
Tryptic peptides and N-glycans were spatially mapped and visualised on formalin-fixed paraffin-embedded (FFPE) endometrial cancer tissue microarrays (TMAs) using an ultrafleXtreme MALDI-ToF/ToF MS instrument (Bruker Daltonics). FFPE egg white was placed either side of each TMA and used as an externa...
ORGANISM(S): Gallus gallus (Chicken) 
2019-12-11 | PXD014310 | Pride
Maldi Ffpe Imaging Egg white 
TranscriptomicsWhite Matter transcriptome in chronic alcoholism
Chronic alcohol consumption can lead to alchohol-related brain damage (ARBD). Despite the well known acute effects of alcohol the mechanism responsible for chronic brain damage is largely unknown. Pathologically the major change is the loss of white matter while neuronal loss is mild and restricted ...
ORGANISM(S): Homo sapiens 
2014-01-04 | E-GEOD-53808 | biostudies-arrayexpress
TranscriptomicsChanges in gene expression in primary human white preadipocytes in response to knockdown of DPP4
Transcriptional profiling of primary human white preadipocytes after infection with lentiviral vector either containing shRNA directed against dipeptidypeptidase 4 (DPP4) or unspecific shRNA as negative control Treatment of cells with DPP4 shRNA or control shRNA was done in 4 biological replicates, ...
ORGANISM(S): Homo sapiens 
2015-11-24 | E-GEOD-75328 | biostudies-arrayexpress
TranscriptomicsTranscriptional co-factor TBLR1 controls lipid mobilization in white adipose tissue
Lipid mobilization (lipolysis) in white adipose tissue (WAT) critically controls lipid turnover and adiposity in humans. While the acute regulation of lipolysis has been studied in detail, the transcriptional determinants of WAT lipolytic activity remain still largely unexplored. Here we show that ...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-43658 | biostudies-arrayexpress
TranscriptomicsGene expression patterns in peripheral blood correlate with the extent of coronary artery disease
Gene expression profile in circulating leukocytes identifies patients with coronary artery disease Peter Sinnaeve, Mark Donahue, Peter Grass, Jacky Vonderscher, David Seo, Pascal Goldschmidt, Christopher Granger Department of Medicine, Duke University, Durham, NC, USA, Novartis Institute for Biome...
ORGANISM(S): Homo sapiens 
2008-10-31 | E-GEOD-12288 | biostudies-arrayexpress
ProteomicsSynechocystis sp. PCC 6803 proteome response to P-deficiency
Lipid droplets (LDs) are well integrated into multiple facets of cellular physiology and potentially represent an effective platform for the engineering of heterologous metabolic pathways. LDs of higher plant chloroplasts, known as plastoglobules (PGs), are critical mediators of stress tolerance thr...
ORGANISM(S): Synechocystis sp. PCC 6803 
2025-05-21 | PXD051903 | Pride
Cyanobacteria Cyanoglobules Phosphorous Phosphate 
TranscriptomicsTranscription profiling of human leukocytes from chronic myeloid leukemia patients exhibiting differing responses to imatinib
This is a class prediction experiment, where the class is the response status to imatinib (also called Gleevec), a drug used to treat patients with chronic myelogenous leukemia (CML). There are two data sets, a training set (from Leipzig, 8 Responders and 5 Non-Responders) and a validation set (fro...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2535 | biostudies-arrayexpress
ProteomicsProteomic dissection of Vanishing white matter pathogenesis
We aimed at gaining more insight into the molecular basis of VWM pathogenesis. Therefore we investigated protein expression patterns in the 2b5ho mouse model using a data-independent mass spectrometry-based quantitative proteomic analysis. The proteome of 4 different brain regions was analyzed at di...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-16 | PXD043872 | Pride
Quantitative proteomics Brain Leukodystrophy Vanishing white matter Disease progression 
TranscriptomicsTranscription profiling of human memory T cells stimulated with Phl p-extract in healthy and allergic individuals
Differential transcriptional response of memory T cells stimulated with Phl p-extract in healthy and allergic individuals.
ORGANISM(S): Homo sapiens 
2006-01-01 | E-MEXP-243 | biostudies-arrayexpress
UnknownCausal Factors of Anxiety and Depression in College Students: Longitudinal Ecological Momentary Assessment and Causal Analysis Using Peter and Clark Momentary Conditional Independence.
Not available
S-EPMC7315365 | biostudies-literature
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