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TranscriptomicsDietary titanium dioxide (E171) increases systemic ROS levels and alters the colon transcriptome – Evidence from a human dietary intervention study
This study provides critical insights into the adverse effects of titanium dioxide (E171) on human gastrointestinal health and its potential molecular mechanisms of action, marking a significant advancement in food toxicology. Through a human dietary intervention study involving 31 participants cons...
ORGANISM(S): Homo sapiens 
2025-09-30 | E-MTAB-15089 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Puga- tBHQ and arsenic treated GCLM-WT and KO mice
Evaluate the protective effect of prior tBHQ treatment from arsenic damage at two dosage levels of arsenic (2 and 20 uM), and compare to the effect of tBHQ or arsenic treatment given alone.
ORGANISM(S): Mus musculus 
2005-12-08 | E-MEXP-371 | biostudies-arrayexpress
TranscriptomicsExpression Array of Lymphoblastoid Cell lines Under Inflammatory Conditions
Comparison of gene expression across 85 cell lines after stimulation with a cocktail of inflammatory cytokines Total RNA extracted from Genotyped Lymphoblastoid cell lines under inflammatory and baseline conditions. 3 biological replicates of stimulated and 2 biological replicates of baseline sample...
ORGANISM(S): Homo sapiens 
2012-09-07 | E-GEOD-25543 | biostudies-arrayexpress
TranscriptomicsMNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL
The phosphorylation of eIF4E1 at serine 209 by MNK1 or MNK2 has been shown to initiate oncogenic mRNA translation, a process that favours cancer development and maintenance. Here, we interrogate the MNK-eIF4E axis in diffuse large B-cell lymphoma (DLBCL) and show a distinct distribution of MNK1 and ...
ORGANISM(S): Homo sapiens 
2014-11-18 | E-GEOD-61691 | biostudies-arrayexpress
TranscriptomicsDistinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma
The mechanistic target of rapamycin, (mTOR) kinase plays a pivotal role in controlling critical cellular growth and survival pathways, and its aberrant induction is implicated in cancer pathogenesis. Therefore, suppression of active mTOR signaling has been of great interest to researchers; several m...
ORGANISM(S): Homo sapiens 
2015-03-03 | E-GEOD-62790 | biostudies-arrayexpress
GenomicsNational Cancer Institute Genome-Wide Association Study of Renal Cell Carcinoma

The National Cancer Institute (NCI) genome-wide association study (GWAS) of renal cell carcinoma (RCC) was conducted to investigate common genetic variants associated with RCC risk. The GWAS includes 1,453 RCC cases and 3,531 controls of European background from 4 studies (3 cohort, 1 case-con...

phs000351.v1.p1 | EGA
TranscriptomicsDeciphering the molecular immune response to COVID-19 using single cell multi-omics
Multi-omics single-cell profiling of surface proteins, gene expression and lymphocyte immune receptors from hospitalised COVID-19 patient peripheral blood immune cells and healthy controls donors. Identification of the coordinated immune cell compositional and state changes in response to SARS-CoV-2...
ORGANISM(S): Homo sapiens 
2021-03-17 | E-MTAB-10026 | biostudies-arrayexpress
UnknownStructure, function and diversity of the healthy human microbiome.
Not available
S-EPMC3564958 | biostudies-literature
UnknownEffect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial.
Not available
S-EPMC5833549 | biostudies-literature
UnknownGrowth differences between North American and European children at risk for type 1 diabetes.
Not available
S-EPMC3335929 | biostudies-literature
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