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MetabolomicsIntegrated Proteomics and Metabolomics Analyses Revealed Potential Phospholipid-Related Biomarkers in Rabbit Atherosclerotic Plaques

BACKGROUND AND AIMS: Atherosclerosis, characterized by dysfunction of lipid metabolism and chronic inflammation, is considered as a metabolic disorder as well as a major contributor to cardiovascular diseases. However, metabolic signatures of atherosclerosis have not been well ex...

2024-09-26 | MTBLS9737 | MetaboLights
MetabolomicsMulti-Omics profiling reveals immunometabolic adaptations underlying disease resilience in indigenous Lueyang Silky Fowl compared to White Leghorns
Sustainable avian production demands genetic strategies beyond vaccines to enhance disease resilience, particularly in indigenous breeds like Lueyang Silky Fowl (LSF), which show superior resistance compared to commercial White Leghorn chickens (WLC) but lack molecular characterization. We hypothesi...
2026-05-27 | MTBLS14590 | MetaboLights
TranscriptomicsTranscription profiling of neutrophils isolated by microfluidics: Clinical Microfluidics for Neutrophil Genomics and Proteomics
Neutrophils play critical roles in modulating the immune response. However, neutrophils have a short circulating half life, are readily stimulated in vitro, and have low levels of cellular mRNA when compared to other blood leukocyte populations. All of these factors have made it difficult to evaluat...
ORGANISM(S): Homo sapiens 
2010-06-16 | E-GEOD-22103 | biostudies-arrayexpress
ProteomicsBlood biomarkers in a cohort of patients with CHRNE-associated congenital myasthenic syndrome
Pathogenic variants in CHRNE encoding the epsilon subunit of acetyl choline receptor (AChR) result in impaired neuromuscular transmission and congenital myasthenic syndromes (CMS). Clinical manifestations include facial, ocular and limb fatigability and weakness, whereby severity of symptoms may var...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054347 | Pride
Cms mirna Cms metabolites Cms biomarkers Plec Cms extracellular vesicles Cms white blood cells Cms amino acids 
ProteomicsHuman immune cell proteomic library
Comprehensive human immune cell proteomic spectral library which contain CD4+T cell, CD8+ T cell, NK cell, B cell, PBMC, Daudi, Jurkat, stimulated Jurkat, Molt-4, Ramos, and THP-1 were generated. This library includes 10,544 proteins groups, and 127,106 peptides.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-12 | MSV000093644 | MassIVE
ProteomicsThe protein organization of a red blood cell
Co-fractionation mass spectrometry and crosslinking mass spectrometry of hemolysate, white ghosts, and other blood cell types.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-29 | MSV000088471 | MassIVE
ProteomicsProteomic studies in VWA1-related neuromyopathy allowed new pathophysiological insights and the definition of blood biomarkers
Pathogenic bi-allelic variants in VWA1, encoding Von Willebrand Factor A domain containing 1 protein localized to the extracellular matrix were recently linked to the manifestation of a neuromuscular disorder with manifestation in child- or adulthood. Myopathological and neurophysiological findings ...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD040226 | Pride
Phgdh Nefm White blood cell proteomics Hnrnpdl Bet1 
ProteomicsProteome analysis of GCN1 CKO mouse inguinal white adipose tissue (iWAT)
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the inguinal white adipose tissue (iWAT), we compared the whole cell proteome of eWAT harvested from GCN1 CKO mice with that ...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030516 | JPOST Repository
ProteomicsGiant Axonal Neuropathy (GAN): Cross-sectional data on phenotypes, genotypes and proteomics signature from a German-Austrian-Swiss cohort
Giant Axon Neuropathy (GAN) is a progressive neurodegenerative disease characterised by involvement of peripheral and central nervous system frequently associated with frizzy hair. The phenotype is caused by bi-allelic variants in the GAN gene, leading to loss of functional gigaxonin proteins.. Thus...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD053070 | Pride
White blood cells Gan Proteomics 
ProteomicsCrosslinking MS of Antibody-HLA-A*11:01
Cross-linking mass spectrometry data of cross-linked antibody to human leukocyte antigen (HLA-A*11:01). For antibodies 2E3, 1E3 and 3H10.
ORGANISM(S): Homo Sapiens (human) 
2023-11-23 | PXD038059 | JPOST Repository
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