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The assembly of nucleosomes by histone chaperones is an important component of transcriptional regulation. Here we have assessed the global roles of the S. pombe HIRA histone chaperone complex. Microarray analysis indicates that inactivation of the HIRA complex results in increased expression of at ...
ORGANISM(S): Schizosaccharomyces pombe 
Maintenance of the correct level and organization of nucleosomes is crucial for genome function. Here we uncover a role for a conserved bromodomain AAA-ATPase, Abo1, in maintenance of nucleosome architecture in fission yeast. Cells lacking abo1+ experience both a reduction and mis-positioning of nuc...
ORGANISM(S): Schizosaccharomyces pombe 
Wildtype and set2delta strains, with samples taken at t=0 and following 30 minutes treatment with 5 µg/ml bleomycin.
ORGANISM(S): Schizosaccharomyces pombe 
Transcription profile of low zinc growth condition in zinc regulatory null mutant
ORGANISM(S): Schizosaccharomyces pombe 
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