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TranscriptomicsPemetrexed alters inflammatory profile in EA.hy 926 cells grown under low-folate conditions.
Pemetrexed is an antifolate drug used in the treatment of lung cancer. EA.hy 926 cells grown under low (Lo) and normal (Hi) folate conditions were treated with PMX. Microarray analysis was used to examine changes in gene expression due to PMX treatment. Hi and Lo cells were grown to confluence and m...
ORGANISM(S): Homo sapiens 
2012-10-03 | E-GEOD-31986 | biostudies-arrayexpress
TranscriptomicsMicroRNAs are required for the feature maintenance and differentiation of brown adipocytes
Brown adipose tissue is specialized to burn lipids for heat generation as a natural defense against cold and obesity. Previous studies established microRNAs as essential regulators of brown adipocyte differentiation, but it remains unknown whether microRNAs are required for the feature maintenance o...
ORGANISM(S): Mus musculus 
2014-08-07 | E-GEOD-60165 | biostudies-arrayexpress
TranscriptomicsRNA Pol III transcriptomes and relationships to Pol II promoters, enhancer-binding factors and chromatin domains
RNA polymerase III transcribes many noncoding RNAs (e.g. tRNAs) important for translational capacity and other functions. Here, we localized RNA polymerase III, alternative TFIIIB complexes (BRF1/2) and TFIIIC in HeLa cells, determining the Pol III transcriptome, defining gene classes, and reveali...
ORGANISM(S): Homo sapiens 
2010-04-14 | E-GEOD-20609 | biostudies-arrayexpress
UnknownMicroRNAs are required for the feature maintenance and differentiation of brown adipocytes.
Not available
S-EPMC4238002 | biostudies-literature
UnknownBody composition and bone health outcomes across positional groups in Netball Super League (NSL) senior and under-21 players; a multi-year cohort study.
Not available
S-EPMC12726998 | biostudies-literature
UnknownEnhancing drug delivery with supramolecular amphiphilic macrocycle nanoparticles: selective targeting of CDK4/6 inhibitor palbociclib to melanoma.
Not available
S-EPMC10872447 | biostudies-literature
UnknownGSK-3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility.
Not available
S-EPMC4543430 | biostudies-literature
UnknownSociety for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events.
Not available
S-EPMC7745688 | biostudies-literature
GenomicsDerivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
The presence of two active X chromosomes (XaXa) is a hallmark of the ground state of pluripotency specific to murine embryonic stem cells (ESCs). Human ESCs invariably exhibit signs of X chromosome inactivation (XCI) and are considered developmentally more advanced than their murine counterparts. W...
ORGANISM(S): Homo sapiens 
2010-05-28 | E-GEOD-21141 | biostudies-arrayexpress
UnknownThe impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study.
Not available
S-EPMC8575157 | biostudies-literature
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