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TranscriptomicsGene expression profiling in acute murine autoimmune hepatitis
The etiology of autoimmune hepatitis is poorly understood but likely involves Th1 cells producing IFN-γ. BALB/c background TGF-β1-/- mice rapidly develop fulminant Th1-mediated autoimmune hepatitis. Our aims are to profile liver gene expression in TGF-β1-/- mice, to identify gene expression pathways...
ORGANISM(S): Mus musculus 
2009-02-28 | E-GEOD-9892 | biostudies-arrayexpress
TranscriptomicsIL13 and CCL2 Drive Disease in an Inflammatory Subset of Scleroderma [cGVHD]
Scleroderma is a lethal and currently irreversible autoimmune disease characterized by widespread tissue fibrosis and vasculopathy. Using cross-species comparative gene expression profiling we show that murine sclerodematous graft-versus-host disease (sclGVHD) approximates an “inflammatory” subset o...
ORGANISM(S): Mus musculus 
2011-06-30 | E-GEOD-17914 | biostudies-arrayexpress
TranscriptomicsFibrotic and Immune Pathway Signatures in Systemic Sclerosis Suggest a Progressive, Multi-step Model of Disease Pathogenesis
Pathway expression analysis in systemic sclerosis revealed key mediators driving pathology within each of the intrinsic gene expression subsets. Genome-wide expression profiling in systemic sclerosis (SSc) has identified four 'intrinsic' subsets of disease (fibroproliferative, inflammatory, limited...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-56308 | biostudies-arrayexpress
UnknownCost-Effectiveness of Treatments after Closed Extraarticular Distal Radius Fractures in Older Adults from the WRIST Clinical Trial.
Not available
S-EPMC7855198 | biostudies-literature
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