Sort   by:  
 Page size 
ProteomicsProteomic Characterization of the Rhesus Macaque Lens Nucleus: Similarity to Human Lens, Age Effects on Protein Solubility, and Trends in Posttranslational Modification
Proteomes of lens nuclei from young (4 years old) and old (15-16 years old) rhesus macaques (Macaca mulatta) were analyzed to determine similarity of the proteomic profile to that of human lenses, age-related differences in protein solubility, and association of various posttranslational modificatio...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2025-09-16 | PXD062952 | Pride
Non-human primates Post-translational modifications Mass spectrometry Eye lens Rhesus macaque Quantitative proteomics Aging 
ProteomicsAge-Related Disruption of the Proteome and Acetylome in Mouse Hearts Correlates with Differential Loss of Function that is Attenuated by SS-31 and NMN
We analyzed the effects of aging on protein abundance and acetylation, as well as the ability of the mitochondrial-targeted drugs SS-31 and NMN to reverse age-related changes, in mouse hearts. Both drugs had a modest effect on restoring the abundance and acetylation of proteins that are lost with ag...
ORGANISM(S): Mus Musculus 
2022-08-02 | PXD027458 | panorama
ProteomicsMouse Heart SS31 Targeted Proteomics
The S-glutathionylation and phosphorylation proteomes of mouse hearts were analyzed using shotgun proteomics methods in order to assess the effects of aging and the ability of mitochondrion-targeted drug SS-31 to reverse age-related changes. There was a nearly universal increase in S-gluthationylati...
ORGANISM(S): Mus Musculus 
2022-03-16 | PXD024247 | panorama
Sort   by:  
 Page size