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GenomicsHSF1 and HSF2 interactions with chromatin during the heat shock response in mouse spermatocytes
Heat shock transcription factors HSF1 and HSF2 both are necessary for proper spermatogenesis, which is disrupted at elevated temperatures. We studied how HSF1 and HSF2 cooperate during the heat shock response in mouse spermatocytes. For this purpose we used ChIP-sequencing. ChIP-Seq analyses reveal...
ORGANISM(S): Mus musculus 
2014-10-07 | E-GEOD-56735 | biostudies-arrayexpress
TranscriptomicsExpression data from control and heat shocked mouse spermatocytes and hepatocytes
In somatic cells elevated temperature induces activation of the heat shock transcription factor 1 (HSF1) what leads to heat shock proteins synthesis and cytoprotection. However, in the male germ cells (spermatocytes) upon HSF1 activation, caspase-3 dependent apoptosis is induced and spermatogenic ce...
ORGANISM(S): Mus musculus 
2012-08-22 | E-GEOD-40248 | biostudies-arrayexpress
TranscriptomicsGenome-wide HSF1 binding sites in control and heat shocked spermatocytes and hepatocytes
In somatic cells elevated temperature induces activation of the heat shock transcription factor 1 (HSF1) what leads to heat shock proteins synthesis and cytoprotection. However, in the male germ cells (spermatocytes) upon HSF1 activation, caspase-3 dependent apoptosis is induced and spermatogenic ce...
ORGANISM(S): Mus musculus 
2012-08-28 | E-GEOD-40390 | biostudies-arrayexpress
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