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TranscriptomicsPI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis
This SuperSeries is composed of the following subset Series: GSE25170: MYC drives resistance to PI3K/mTOR targeted inhibition (Sty SNP array) GSE25172: MYC drives resistance to PI3K/mTOR targeted inhibition (gene expression) Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-09-13 | E-GEOD-25173 | biostudies-arrayexpress
UnknownDual suppression of the cyclin-dependent kinase inhibitors CDKN2C and CDKN1A in human melanoma.
Not available
S-EPMC3490842 | biostudies-literature
UnknownInternet-Administered Emotional Awareness and Expression Therapy for Somatic Symptom Disorder With Centralized Symptoms: A Preliminary Efficacy Trial.
Not available
S-EPMC7928393 | biostudies-literature
TranscriptomicsMYC drives resistance to PI3K/mTOR targeted inhibition (Sty SNP array)
Genomic copy-number changes were measured using 250K StyI SNP arrays after selection of cells to enrich for resistance to BEZ235. Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted using Qiagen DNeasy from engineered human cell-lines. Resulting alteratio...
ORGANISM(S): Homo sapiens 
2011-08-30 | E-GEOD-25170 | biostudies-arrayexpress
Proteomicssuppression of PPARGC1A causes collateral sensitivity to HMGCR-inhibitor within BRAFi-treatement resistant melanoma
We aimed to identify the potential proteins as a collateral vulnerability within PGC1a-suppressed BRAF-inhibitor resistant melanomas, and the potential mechanisms behind this including their abundancy and cellular distribution.
ORGANISM(S): Homo sapiens (Human) 
2023-06-09 | PXD041952 | Pride
Melanoma statin ppargc1a statin 
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