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GenomicsAnalysis of MIZ1, MYC-ER and MYC-ERVD binding sites in MCF10A cells
Oncogenic levels of Myc expression sensitize cells to multiple apoptotic stimuli and this protects long-lived organisms from cancer development. How cells discriminate physiological from supra-physiological levels of Myc is largely unknown. Here we show that induction of apoptosis by Myc in breast e...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-59146 | biostudies-arrayexpress
ProteomicsPhosphoprojekt - Comparison of Alternative MS/MS and Bioinformatics Approaches for Confident Phosphorylation Site Localization
Not available
ORGANISM(S): Homo sapiens (Human) 
2014-03-26 | PRD000284 | Pride
TranscriptomicsMYC-ER and MYC-ER V394D induced gene expression changes in MCF10A cells
Oncogenic levels of Myc expression sensitize cells to multiple apoptotic stimuli and this protects long-lived organisms from cancer development. How cells discriminate physiological from supra-physiological levels of Myc is largely unknown. Here we show that induction of apoptosis by Myc in breast e...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-59145 | biostudies-arrayexpress
UnknownHalogenation-Guided Chemical Screening Provides Insight into Tjipanazole Biosynthesis by the Cyanobacterium Fischerella ambigua.
Not available
S-EPMC7497240 | biostudies-literature
TranscriptomicsOncogenic Myc levels activate and repress specific genes to form characteristic expression profiles in human tumors
Myc was depleted in HeLa cells (ATCC CRL-1934) with an shRNA and the resulting expression profile changes mapped via microarrays. This study is the equivalent of E-MTAB-1524 . E-MTAB-1524 has been replaced by E-MTAB-1886.
ORGANISM(S): Homo sapiens 
2014-07-11 | E-MTAB-1886 | biostudies-arrayexpress
UnknownCharacterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules.
Not available
S-EPMC2132928 | biostudies-literature
GenomicsBIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues
C-MYC (henceforth MYC) is one of the most frequently overexpressed oncogenes in human cancer and even modestly deregulated MYC expression can initiate ectopic proliferation in many post-mitotic, terminally differentiated cell types in vivo. Metazoan organisms have consequently evolved a number of me...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-59001 | biostudies-arrayexpress
UnknownTime-lapse microscopic observation of non-dividing cells in cultured human osteosarcoma MG-63 cell line.
Not available
S-EPMC5884383 | biostudies-literature
ModelsDallePezze2016 - Activation of AMPK and mTOR by amino acids
DallePezze2016 - Activation of AMPK and mTOR by amino acids (Model 3) This model is as described in the Supplementary Software 3 of the reference publication: SBML model similar to Model S2, but including a more complex p70-S6K module. This model is described in the article: A...
2024-09-02 | BIOMD0000000640 | BioModels
ModelsDallePezze2016 - Activation of AMPK and mTOR by amino acids (Model 1)
DallePezze2016 - Activation of AMPK and mTOR by amino acids (Model 1) This model is as described in Supplementary Software 2 of the reference publication: SBML model including only the canonical amino acid input on mTORC1. This model is described in the article: A systems study reveals ...
2017-05-18 | MODEL1705030000 | BioModels
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