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TranscriptomicsThe histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival
We profiled basal and bicuculline+4-AP inducible mRNA expression in cultured mouse hippocampal neurons with or without viral shRNA mediated knockdown of Kdm6b We harvested mRNA from neurons under four conditions (pLKO vector/treatment control, pLKO vector/3hr bicuculline+4AP, Kdm6b knockdown/treatme...
ORGANISM(S): Mus musculus 
2014-06-12 | E-GEOD-58398 | biostudies-arrayexpress
GenomicsChromatin accessibility profiling of developing cerebellar granule neurons identifies novel neuronal enhancers and reveals a role for Zic transcription factors in neuronal maturation
To identify chromatin mechanisms of neuronal differentiation, we characterized the relationship between chromatin accessibility and gene expression in cerebellar granule neurons (CGNs) of the developing mouse. We used DNase-seq to globally map accessibility of cis-regulatory elements and RNA-seq to ...
ORGANISM(S): Mus musculus 
2015-02-27 | E-GEOD-60731 | biostudies-arrayexpress
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