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TranscriptomicsIdentification of novel metastases-suppressor genes involved in lung cancer brain metastases formation.
Initial screening for potential metastases suppressors down regulated by methylation was performed using lung cancer cell line models specific for site-specific metastasation. Gene expression profiling and qRT-PCR validations were conducted on tumor tissues from primary lung cancer (LC) and brain me...
ORGANISM(S): Homo sapiens 
2014-11-18 | E-GEOD-57492 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of human brain metastases and primary breast carcinomas
This study comprises arrayCGH data from the University clinic Eppendorf (UKE) in Hamburg. The array platform being used is the VUMC v30 30k Oligo chip
ORGANISM(S): homo sapiens 
2012-03-08 | E-MTAB-354 | biostudies-arrayexpress
TranscriptomicsRAI2 overexpression in MDA-MB231
MDA-MB231 cells were transfected with control vector, RAI2-overexpression vector, or vector with RAI2-4A, which has a mutated interaction domain w.r.t. CtBP/CtBP2 Three replicates each of control condition, RAI2 overexpression or RAI2-4A overexpression.
ORGANISM(S): Homo sapiens 
2015-06-15 | E-GEOD-65489 | biostudies-arrayexpress
ProteomicsHERC5 alters mitochondrial energy metabolism pathways in NSCLC
In 2020, lung cancer remains the most diagnosed entity among men and third most among women, causing approximately 1.8 million deaths worldwide with an estimated 31.5% of new cases in men and 14.6% in women, respectively (1). Moreover, metastasized non-small cell lung cancer (NSCLC) continues to be ...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD045563 | Pride
Nsclc Oxphos Cancer metabolism 
TranscriptomicsmRNA-seq of HCC1954 siControl and siRNF40
The analysis of genes affected upon RNF40 knockdown in HCC1954 cells
ORGANISM(S): Homo sapiens 
2020-11-16 | E-MTAB-9234 | biostudies-arrayexpress
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