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ProteomicsP-VIS: internally-controlled validation of mass spectrometry-based peptide identifications
Peptide-Spectrum Match (PSM) Validation with Internal Standards (P-VIS) is an objective approach to validating individual PSMs. A biological sample is analyzed by LC-MS/MS and the data are searched using a traditional approach such as a database search or de novo sequencing. A PSM of interest is ide...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-09-21 | PXD020901 | Pride
Peptidomics Hybrid insulin peptides Peptide-spectrum match Post-translational modification Validation Immunotherapy Peptide splicing Immunopeptidomics 
ProteomicsIdentification of HIPs in the islets of mice and non-diabetic human donors
Hybrid insulin peptides (HIPs) result from the linkage of an insulin C-peptide fragment and another peptide via a traditional peptide bond to generate a sequence that is not encoded in the genome. Here, we sought to identify HIPs naturally present in the pancreatic islets of non-obese diabetic (NOD)...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-01-07 | PXD011606 | Pride
Hybrid insulin peptides (hips) Pancreatic islets 
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