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TranscriptomicsTranscriptional profiling of Hoxa9-expanded hematopoietic cells expressing distinct TALE genes
Primary murine hematopoietic cells were retrovirally transduced with Hoxa9 cDNA, expanded in vitro before undergoing secondary infection with the cDNA of Meis1, Prep1 and the Prep1-MC mutant. RNA was extracted and transcriptomes were analyzed. Background corrections and normalisations were performe...
ORGANISM(S): Mus musculus 
2011-09-08 | E-MTAB-671 | biostudies-arrayexpress
no omics definedHigh throughput sequenceing of fission yeast to survey the dynamic repertoire of a eukaryotic transcriptome at the single nucleotide resolution
Recent data from several organisms indicate that the transcribed portions of genomes are larger and more complex than expected, and many functional properties of transcripts are not based on coding sequences but on regulatory sequences in untranslated regions or non-coding RNAs. Alternative start a...
ORGANISM(S): Schizosaccharomyces pombe 
2008-12-10 | E-MTAB-5 | biostudies-arrayexpress
TranscriptomicsAlternative splicing controlled by heterogeneous nuclear ribonucleoprotein L (hnRNP L) regulates development, proliferation and migration of thymic pre-T cells
The regulation of post-transcriptional modifications of pre-mRNA by alternative splicing is important for cellular function, development and immunity The receptor tyrosine phosphatase CD45, which is expressed on all hematopoietic cells, is known for its role in the development and activation of T ce...
ORGANISM(S): Mus musculus 
2012-04-23 | E-GEOD-33306 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of wide type fission yeast to identify intronic and exonic DNA regions with respect to RNA polymerase II occupancy, histone density and H3K36me3 patterns
Differential marking of intronic and exonic DNA regions with respect to RNA polymerase II occupancy, histone density and H3K36me3 patterns in fission yeast
ORGANISM(S): Schizosaccharomyces pombe 
2011-03-16 | E-TABM-946 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of leukemia cells derived from mice
Transcriptome analysis of leukemia cells
ORGANISM(S): Mus musculus 
2011-01-18 | E-TABM-947 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse wild type and Baf250a delta/delta primary stromal cell cultures
Global gene expression profiles of primary Baf250a delta/delta and WT FL-derived stromal cell cultures.

Normalized data files with gene level identifiers are available as additional files on the FTP site for this experiment. Background corrections and normalisations were performed using RMA ...
ORGANISM(S): Mus musculus 
2010-06-05 | E-TABM-990 | biostudies-arrayexpress
TranscriptomicsAnalysis of Fetal liver cells from hnRNP L KO mice
The regulation of post-transcriptional modifications of pre-mRNA by alternative splicing is important for cellular function, development and immunity. To investigate the role of hnRNP L in this process, we have generated conditional hnRNP L knockout mice carrying floxed alleles in order to generate ...
ORGANISM(S): Mus musculus 
2013-12-31 | E-GEOD-33815 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast under multiple conditions, including exponential proliferation, meiotic differentiation and environmental stress, and in RNA processing mutants
Recent data from several organisms indicate that the transcribed portions of genomes are larger and more complex than expected, and many functional properties of transcripts are not based on coding sequences but on regulatory sequences in untranslated regions or non-coding RNAs. Alternative start a...
ORGANISM(S): Schizosaccharomyces pombe 
2008-05-18 | E-MTAB-18 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of fission yeast to determine Yox1 and cdc10 transcription factor binding sites
Transcription profiling of fission yeast /yox1/ deletion and genome wide location analysis of Yox1p and Cdc10p transcription factors reveal a negative feedback interaction: /yox1 /is transcriptionally activated by MBF, and Yox1p in turn transcriptionally represses the MBF target genes (including /yo...
ORGANISM(S): Schizosaccharomyces pombe 
2009-08-25 | E-TABM-647 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast wild type and yox1 mutant strains
Transcription profiling of fission yeast /yox1/ deletion and genome wide location analysis of Yox1p and Cdc10p transcription factors reveal a negative feedback interaction: /yox1 /is transcriptionally activated by MBF, and Yox1p in turn transcriptionally represses the MBF target genes (including /yo...
ORGANISM(S): Schizosaccharomyces pombe 
2009-08-20 | E-TABM-646 | biostudies-arrayexpress
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