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MetabolomicsA comprehensive multiomic analysis reveals metabolic reprogramming underlying human Fontan-associated liver disease

BACKGROUND: Single ventricle congenital heart disease (SVCHD) is a severe form of cardiac malformation in which there is only one functional ventricle. The Fontan operation is the current standard of care for SVCHD. Almost all patients who have undergone the Fontan operation develop liver fibrosi...

2024-12-13 | MTBLS10782 | MetaboLights
TranscriptomicsExpression profiling of cotton (Gossypium barbadense L. Pima S7) fiber transcriptome during the development
To gain novel insights into the molecular mechanisms underlying Pima cotton fiber quality, expression profiling of the Pima fiber transcriptome was performed as a function of development. The profiling was performed at 6 developmental time points: 8, 11, 14, 17, 21, and 24dpa. The expression profili...
ORGANISM(S): Gossypium barbadense 
2010-05-26 | E-GEOD-11689 | biostudies-arrayexpress
TranscriptomicsExpression profiling of cotton (Gossypium hirsutum L. TM1) fiber transcriptome during the development
In order to study gene expression at the genomic level during elongation and secondary cell wall synthesis of upland cotton fiber, oligonucleotide microarrays were employed. RNA was isolated from fibers in 7 different time points beginning prior to peak fiber expansion, continuing through terminatio...
ORGANISM(S): Gossypium hirsutum 
2010-05-26 | E-GEOD-11693 | biostudies-arrayexpress
UnknownLigand-enforced intimacy between a gold cation and a carbenium ion: impact on stability and reactivity.
Not available
S-EPMC8179465 | biostudies-literature
UnknownShort Italian Wilkins Rate of Reading Test for repeated-measures designs in optometry and neuropsychology.
Not available
S-EPMC11611593 | biostudies-literature
TranscriptomicsTime of day shapes the Arabidopsis drought transcriptomes
Under natural conditions, plants experience episodes of drought for periods of days or longer. Plants respond to drought stress by reconfiguring their transcriptome activity. Transcriptome changes in response to drought are dynamic, and are likely to be shaped by mitigating factors such as diel sign...
ORGANISM(S): Arabidopsis thaliana 
2010-07-30 | E-GEOD-19700 | biostudies-arrayexpress
UnknownCampylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail.
Not available
S-EPMC4972205 | biostudies-literature
UnknownDomain cross-talk within a bifunctional enzyme provides catalytic and allosteric functionality in the biosynthesis of aromatic amino acids.
Not available
S-EPMC6442060 | biostudies-literature
ProteomicsValidation of alternatively spliced protein isoforms in human mesenchymal stem cells
Alternative splicing of mRNA diversifies the function of human proteins, with tissue- and cell-specific protein isoforms being the most difficult to validate. While transcriptomic experiments enable the detection of many alternatively spliced transcripts, it is not known if these transcripts have pr...
ORGANISM(S): Homo sapiens (Human) 
2015-05-20 | PXD001449 | Pride
Human Mesenchymal stem cell Lc-ms/ms 
TranscriptomicsThe evolution of spinable cotton fiber entailed prolonged development and a novel metabolism
exceptional example of evolutionary innovation is the single-celled seed trichome in Gossypium ("cotton fiber"). We have used fiber development in Gossypium as a system to understand how morphology can rapidly evolve. Fiber has undergone considerable morphological changes between the short, tightly...
ORGANISM(S): Gossypium herbaceum 
2010-06-25 | E-GEOD-10228 | biostudies-arrayexpress
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