Wilkins Benjamin B

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A comprehensive multiomic analysis reveals metabolic reprogramming underlying human Fontan-associated liver disease

BACKGROUND: Single ventricle congenital heart disease (SVCHD) is a severe form of cardiac malformation in which there is only one functional ventricle. The Fontan operation is the current standard of care for SVCHD. Almost all patients who have undergone the Fontan operation develop liver fibrosi...

2024-12-13 | MTBLS10782 | MetaboLights

Proteomic analysis of clear cell renal cell carcinoma tissue versus matched normal kidney tissue

We analyzed 84 tumor/normal pairs (177 total) using standard shotgun proteomic techniques in order to characterize the molecular landscape of clear cell renal cell carcinoma (ccRCC) and interrogated changes in protein abundance and biological pathways with ccRCC grade. These tissues were distributed...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079972 | MassIVE

Leveraging the Expertise of the CTSA Program to Increase the Impact and Efficiency of Clinical Trials.

Not available

S-EPMC10773966 | biostudies-literature

Whole genome sequence analysis of blood lipid levels in >66,000 individuals.

Not available

S-EPMC9553944 | biostudies-literature

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.

Not available

S-EPMC10008172 | biostudies-literature

A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk.