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TranscriptomicsVariations in stress sensitivity and genomic expression in diverse S. cerevisiae strains (gene expression)
Gene expression variation was measured in 17 non-laboratory strains compared to the sequenced S288c lab strain Keywords: Gene expression comparisons in different yeast strains Each strain was grown in at least biological triplicate to log phase in rich (YPD) medium. Extracted total RNA was compared...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-10268 | biostudies-arrayexpress
TranscriptomicsVariations in stress sensitivity and genomic expression in diverse S. cerevisiae strains (CGH)
Gene expression variation was measured in 17 non-laboratory strains compared to the sequenced S288c lab strain Keywords: comparative genomic hybridizations (CGH) comparing different yeast strains Each strain was grown in at least biological triplicate to log phase in rich (YPD) medium. Extracted to...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-10267 | biostudies-arrayexpress
TranscriptomicsThe Histone Deacetylase Rpd3p Coordinates Transient Changes in Genomic Expression in Response to Acute Stress
To characterize the role of chromatin remodeling proteins in mediating stress-activated expression changes, whole-genome expression was followed in wild-type and mutant cells (including strains lacking the histone deacetylase Rpd3p, associated Rpd3p proteins, and the transcription factors Msn2p and ...
ORGANISM(S): Saccharomyces cerevisiae 
2009-05-20 | E-GEOD-9108 | biostudies-arrayexpress
TranscriptomicsInferring the stress-activated signaling network in yeast through multi-omic data integration
Transcriptome profiling of yeast mutant strains responding to 0.7M NaCl treatment for 30 minutes. This study identified affected genes in each mutant and used it to computationally infer the complete NaCl-activated signaling network in yeast. Two-color fluorescence arrays reporting on mRNA abundanc...
ORGANISM(S): Saccharomyces cerevisiae 
2014-12-03 | E-GEOD-51844 | biostudies-arrayexpress
ProteomicsMechanisms of microbial magnetite oxidation by Sideroxydans lithotrophicus ES-1
Iron-oxidizing bacteria are widely found in natural and man-made environments where they influence varied biogeochemical cycles. Despite their prevalence, the mechanisms and Fe(II) substrates used by these organisms remain understudied. To date, there has been limited exploration of the ability of i...
ORGANISM(S): Sideroxydans Lithotrophicus (ncbitaxon:63745) 
2024-01-04 | MSV000093770 | MassIVE
TranscriptomicsRNA-binding protein AUF1 promotes myogenesis by regulating MEF2C expression levels
The mammalian RNA-binding protein AUF1 (AU-binding factor 1, also known as heterogeneous nuclear ribonucleoprotein D, hnRNP D) binds to numerous mRNAs and influences their post-transcriptional fate. Given that many AUF1 target mRNAs encode muscle-specific factors, we investigated the function of AU...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-58259 | biostudies-arrayexpress
GenomicsThe Ovarian Cancer Association Consortium Data Access Committee
Data Access Committee EGAC00001000616
EGAC00001000616 | EGA
TranscriptomicsIsoform diversity and regulation in peripheral and central neurons revealed through RNA-Seq
To fully understand cell type identity and function in the nervous system there is a need to understand neuronal gene expression at the level of isoform diversity. Here we applied Next Generation Sequencing of the transcriptome (RNA-Seq) to purified sensory neurons and cerebellar granular neurons (C...
ORGANISM(S): Mus musculus 
2012-01-17 | E-GEOD-33343 | biostudies-arrayexpress
GenomicsGenome Landscape of Primary Pancreatic Ductal Adenocarcinoma
The purpose of the Australian ICGC Pancreatic Cancer Genome Sequencing Initiative study is to identify the common driving mutations underlying the initiation and development of Pancreatic Adenocarcinoma in a large cohort of pancreatic cancer patients (n=350). Matched genome sequences will be generat...
EGAS00001000154 | EGA
GenomicsGenome Sequencing of Pancreatic Ductal Adenocarcinoma at The Human Genome Sequencing Center of Baylor College of Medicine (HGSC-BCM)

Pancreatic ductal adenocarcinomas (PDAC) is the 11th most common cancer in the USA but the 4th in fatalities. The onset and progression of cancer is driven by extensive rearrangement and mutation of the genome. We combined our capability to capture and enrich exome DNA with the next generation se...

phs000516.v1.p1 | EGA
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