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TranscriptomicsTranscription profiling of mouse fibroblasts expressing the 57Bl/6 Ah-receptor vs. Ahr-/- fibroblasts synchronized at G0/G1, S-phase, and in exponential growth
Role of the Ah-receptor in cell cycle regulation. Mouse fibroblasts expressing the Ah-receptor of C57Bl/6 mice under the regulation of the Tet*Off system were compared to Ahr-/- fibroblasts synchronized at G0/G1, S-phase, or in exponential growth.
ORGANISM(S): Mus musculus 
2007-08-05 | E-MEXP-996 | biostudies-arrayexpress
MetabolomicsQuantitative metabolomic analysis of changes in the lens and aqueous humor under development of age-related nuclear cataract

INTRODUCTION: Metabolites are essential for the proper functioning of the eye lens, they either enter the lens from the aqueous humor (AH), or are synthesized in the lens epithelium. Antioxidants, osmolytes and UV filters are especially important for the lens protection, and thei...

2022-11-07 | MTBLS740 | MetaboLights
TranscriptomicsLack of hepatic response of microRNA in mice following DB[a,h]A exposure (Agilent miRNA)
Dibenzo[a,h]anthracene DB[a,h]A is a polycyclic aromatic hydrocarbon potent carcinogen. Few studies have investigated the role of DB[a,h]A on mRNA and miRNA expression. In this study a 10-week old male MutaTM Mouse were exposed to 6.25, 12.5, and 25 mg/kg/day DB[a,h]A by oral gavage for 28 cons...
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-35195 | biostudies-arrayexpress
TranscriptomicsLack of hepatic response of microRNA in mice following DB[a,h]A exposure (Agilent expression)
Dibenzo[a,h]anthracene DB[a,h]A is a polycyclic aromatic hydrocarbon potent carcinogen. Few studies have investigated the role of DB[a,h]A on mRNA and miRNA expression. In this study a 10-week old male MutaTM Mouse were exposed to 6.25, 12.5, and 25 mg/kg/day DB[a,h]A by oral gavage for 28 cons...
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-35215 | biostudies-arrayexpress
TranscriptomicsLack of hepatic response of microRNA in mice following DB[a,h]A exposure
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-07-02 | E-GEOD-35509 | biostudies-arrayexpress
TranscriptomicsAdult mouse liver following benzo(a)pyrene (BaP) treatment: miRNA and mRNa profiling
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2010-10-18 | E-GEOD-18841 | biostudies-arrayexpress
UnknownReciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia.
Not available
S-EPMC3838485 | biostudies-literature
MetabolomicsEvaluation of extraction solvents for untargeted metabolomics analysis of enrichment reactor cultures performing enhanced biological phosphorus removal (EBPR)

INTRODUCTION: The extraction solvent mixtures were optimized for untargeted metabolomics analysis of microbial communities from two laboratory scale activated sludge reactors performing enhanced biological phosphorus removal (EBPR).

OBJECTIVE: To develop a ...

2019-08-16 | MTBLS884 | MetaboLights
MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
TranscriptomicsGene expression changes induced by Benzo[a]pyrene (BaP) in human breast carcinoma cell line MCF-7 in different phases of the cell cycle
Benzo[a]pyrene (BaP) is a widespread environmental genotoxic carcinogen that damages DNA by forming adducts. This damage with along the activation of the aryl hydrocarbon receptor (AHR) induces complex transcriptional responses in cells. To investigate whether human cells are more susceptible to BaP...
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-26917 | biostudies-arrayexpress
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