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TranscriptomicsComparative genomic hybridization of 30 ovarian cancer cell lines reveals amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer
DNA from 30 cultured ovarian cancer cell lines was extracted with Promega kits and hybridize to arrays. Arrays comprised of 1860 BACs selected to include genes known to be involved in cancer pathogenesis and 400 BACs selected to tile across 13 Mbp at 3q26, 15 Mbp at 8q24, and 30 Mbp at 20q centered ...
ORGANISM(S): Homo sapiens 
2007-06-04 | E-TABM-246 | biostudies-arrayexpress
TranscriptomicsThe effect of BrdU on gene expression profiles of B6C3F1 mice treated with furan
Furan is a mouse and rat hepatocarcinogen. We sought to determine the dose-dependent changes in gene expression upon exposure of B6C3F1 mice to furan in order to better understand furan’s mode of action. In this study we examined the transcriptional response in liver tissue of female B6C3F1 mice to ...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-54078 | biostudies-arrayexpress
TranscriptomicsCell death and regenerative proliferation pathways in hepatocellular carcinoma: The effect of furan on B6C3F1 mouse global gene expression in liver
Furan is a mouse and rat hepatocarcinogen. We sought to determine the dose-dependent changes in gene expression upon exposure of B6C3F1 mice to furan in order to better understand furan’s mode of action. Adult female B6C3F1 mice were exposed to 1, 2, 4 or 8 mg/kg bw furan or vehicle control (corn oi...
ORGANISM(S): Mus musculus 
2014-01-10 | E-GEOD-48644 | biostudies-arrayexpress
TranscriptomicsPARP1- and CTCF-mediated interactions between active and repressed chromatin at the lamina promote oscillating transcription
Transcriptionally active and inactive chromatin domains tend to segregate into separate sub-nuclear compartments to maintain stable expression patterns. However, we have uncovered here an inter-chromosomal network connecting active loci enriched in circadian genes to repressed lamina-associated doma...
ORGANISM(S): Homo sapiens 
2015-08-27 | E-GEOD-26880 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation in yeast for different affinity-tagged strains (two genotypes compared with wild type)
RNA immunoprecipitation from different affinity-tagged strains. Each hyb compared to a common total RNA.
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-09 | E-MEXP-208 | biostudies-arrayexpress
TranscriptomicsmRNA expression profiling of mouse microvasculature
Combination of reverse- and chemical genetic screens reveals a network of novel angiogenesis inhibitors and targets Drug target identification and validation are bottlenecks in the drug discovery process. Accordingly there is a need to develop new methods to facilitate the development of much-nee...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-10035 | biostudies-arrayexpress
UnknownMortality after surgery in Europe: a 7 day cohort study.
Not available
S-EPMC3493988 | biostudies-literature
UnknownGlobal, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.
Not available
S-EPMC4202387 | biostudies-literature
UnknownFactors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial.
Not available
S-EPMC11187765 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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