Benzo[a]pyrene (BaP) is a widespread environmental genotoxic carcinogen that damages DNA by forming adducts. This damage with along the activation of the aryl hydrocarbon receptor (AHR) induces complex transcriptional responses in cells. To investigate whether human cells are more susceptible to BaP...
Genomic DNA samples were extracted from microdissected colorectal tumour tissue and then compared against normal DNA extracted from the peripheral blood from the same patients. 53 Normal/Tumor matched samples.
