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The objective of the current study was to evaluate the performance of frequently used E. coli K-12 strains HMS174 and RV308 in the context of industrial cultivations. To meet this objective, we carried out batch cultivations with high-glucose media in computer-controlled bioreactors and applied tran...
ORGANISM(S): Escherichia coli 
Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription factor that plays an important role in breast cancer. Estrogen-dependent gene regulation by ERalpha can be mediated by interaction with other DNA-binding proteins, such as activator protein-1 (AP-1). The nature of such interaction...
ORGANISM(S): Homo sapiens 
Expression of the lim-homeodomain transcription factor is required for sustained maintenance of heamatopoietic stem cell like cells in undifferentiated form durng in vitro culturing. Cell lines were created from the mouse embryonic stem (ES) cell line, Ainv15. The gene Lhx2 was introducted into thes...
ORGANISM(S): Mus musculus 
The cyclin D1 oncogene encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the Rb protein and promotes progression through G1 to S phase of the cell cycle. Several prostate cancer cell lines and a subset of primary prostate cancer samples have increased cyclin D1 prote...
ORGANISM(S): Homo sapiens 
The objective of the current study was to evaluate the performance of frequently used E. coli BL21 in the context of industrial cultivations. To meet this objective, we carried out batch cultivations with high-glucose media in computer-controlled bioreactors and applied transcriptome analysis to int...
ORGANISM(S): Escherichia coli 
In patients with primary breast cancer, neoadjuvant chemotherapy with doxorubicin plus pemetrexed followed by docetaxel (AP-D) is associated with a pathologic complete response (pCR) rate of 16.5%, and doxorubicin plus cyclophosphamide followed by docetaxel (AC-D) is associated with a pCR rate of 20...
ORGANISM(S): Homo sapiens 
Insights into mechanisms involved during intra-medullary myeloma progression could be helpful in the better understanding of this disease and in the development of new therapeutical strategies. Herein gene expression profile of multiple myeloma (MM) cells during intra-medullary progression was inves...
ORGANISM(S): Mus musculus 
Whole blood was collected from cynomolgus macaques into PAXgene Blood RNA tubes (PreAnalytiX) and stored at –20 °C until RNA extraction. Animals were divided into three vaccine groups: mRNA influenza vaccine (n = 5), Vaxigrip (n = 4), and Fluad (n = 5). Samples were taken at baseline (0 h), 24 h pos...
ORGANISM(S): Macaca mulatta 
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