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GenomicsDDM1 and RdDM are the major regulators of transposon DNA methylation in Arabidopsis
Eukaryotic DNA methylation is found in silent transposable elements and active genes. Nucleosome remodelers of the DDM1/Lsh family are thought to be specifically required to maintain transposon methylation, but the reason for this is unknown. Here, we find that a chromatin gradient that extends from...
ORGANISM(S): Arabidopsis thaliana 
2013-04-17 | E-GEOD-41302 | biostudies-arrayexpress
UnknownHominin glacial-stage occupation 712,000 to 424,000 years ago at Fordwich Pit, Old Park (Canterbury, UK).
Not available
S-EPMC12507691 | biostudies-literature
TranscriptomicsMolecular prediction of gastrulation stages with small extra-embryonic gene-set
Axis specification in mouse is determined by a sequence of reciprocal interactions between embryonic and extra-embryonic tissues so that a few extra-embryonic genes appear as ‘patterning’ the embryo. Considering these interactions as essential, but lacking in most mammals the genetically driven appr...
ORGANISM(S): Bos taurus 
2010-06-24 | E-GEOD-13013 | biostudies-arrayexpress
UnknownElectronic Delivery of Pain Education for Chronic Overlapping Pain Conditions: A Prospective Cohort Study.
Not available
S-EPMC8677459 | biostudies-literature
UnknownPotentiation of amyotrophic lateral sclerosis (ALS)-associated TDP-43 aggregation by the proteasome-targeting factor, ubiquilin 1.
Not available
S-EPMC2658102 | biostudies-literature
UnknownA model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis.
Not available
S-EPMC4634366 | biostudies-literature
UnknownPatient-Customized Oligonucleotide Therapy for a Rare Genetic Disease.
Not available
S-EPMC6961983 | biostudies-literature
UnknownA multi-institutional phase 2 study of neoadjuvant gemcitabine and oxaliplatin with radiation therapy in patients with pancreatic cancer.
Not available
S-EPMC4174603 | biostudies-literature
MetabolomicsELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease with distinct molecular subtypes described as classical/progenitor and basal-like/squamous PDAC. We hypothesized that integrative transcriptome and metabolome approaches can identify candidate genes whose inactivation contributes to ...
2024-04-02 | MTBLS9418 | MetaboLights
UnknownGenome-wide linkage analysis of obsessive-compulsive disorder implicates chromosome 1p36.
Not available
S-EPMC3437244 | biostudies-literature
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