Sort   by:  
 Page size 
TranscriptomicsTet1 and hydroxymethylcytosine in transcription and DNA methylation fidelity (Affymetrix gene expression data)
Enzymes catalyzing the methylation of the 5-position of cytosine (mC) have essential roles in regulating gene expression, genome stability, and maintaining cellular identity. Recently Tet1, which is highly expressed in embryonic stem (ES) cells, was found to oxidize the methyl group of mC converting...
ORGANISM(S): Mus musculus 
2011-04-13 | E-GEOD-24842 | biostudies-arrayexpress
TranscriptomicsIntegrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation [DGE]
5-methylcytosine (5-mC) can be oxidized to 5-hydroxymethylcytosine (5-hmC). Genome-wide profiling of 5-hmC thus far indicated 5-hmC may not only be an intermediate form of DNA demethylation but could also constitute an epigenetic mark per se. We describe a cost-effective and selective method to dete...
ORGANISM(S): Homo sapiens 
2012-12-20 | E-GEOD-40953 | biostudies-arrayexpress
GenomicsEHMT1 and EHMT2 inhibition induce fetal hemoglobin expression
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-11-02 | E-GEOD-71422 | biostudies-arrayexpress
TranscriptomicsEHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq]
Using UNC0638 and genetic assays to inhibit EHMT1/2 and derepress fetal hemoglobin in adult hematopoietic cells. RNA-Seq in primary adult human erythroid cells treated with UNC0638 or the vehicle control (DMSO) in biological triplicates.
ORGANISM(S): Homo sapiens 
2015-11-02 | E-GEOD-71421 | biostudies-arrayexpress
UnknownTranscriptional regulation by Asf1: new mechanistic insights from studies of the DNA damage response to replication stress.
Not available
S-EPMC3044965 | biostudies-literature
UnknownSingle aromatic residue location alters nucleic acid binding and chaperone function of FIV nucleocapsid protein.
Not available
S-EPMC4252577 | biostudies-literature
TranscriptomicsAre Non-animal Systemic Safety Assessments Protective: A Toolbox and Workflow
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15258 | biostudies-arrayexpress
UnknownExcessive burden of lysosomal storage disorder gene variants in Parkinson's disease.
Not available
S-EPMC5841393 | biostudies-literature
TranscriptomicsMonkeypox and Vaccinia infection of cultured human cells
We analyzed effects of monkeypox (MPX) and vaccinia (VAC) infection on cultured human cells. Our custom-designed arrays contain >18,000 human genes as well as genes for each open reading frame of MPX and VAC. A reference experiement design type is where all samples are compared to a common referenc...
ORGANISM(S): Homo sapiens 
2008-07-17 | E-GEOD-11234 | biostudies-arrayexpress
UnknownWhole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants 33 to 35 Weeks' Gestation: A Randomized Clinical Trial.
Not available
S-EPMC11851295 | biostudies-literature
Sort   by:  
 Page size