Williams Nita N

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Gene expression profiling of in vitro derived induced and natural FOXP3+ regulatory T cells and ex-iTreg cells in the mouse

Induced Treg (iTreg) cells are essential for tolerance and can be used therapeutically, yet their stability in vivo and mechanisms of suppression are unresolved. Here, we used a treatment model of colitis to examine the role of autologous IL-10 in iTreg cell function. Mice treated with IL-10+/+ iTr...

ORGANISM(S): Mus musculus

2012-12-06 | E-GEOD-35543 | biostudies-arrayexpress

Gene expression profiling of in vivo derived induced and natural FOXP3+ regulatory T cells in the mouse

The relative contribution of induced and natural Foxp3+ regulatory T cells (iTreg and nTreg cells, respectively) to the maintenance of tolerance is unknown. We examined their respective roles by in vivo adoptive transfer immunotherapy of newborn Foxp3-deficient BALB/c mice. Survival, weight gain, ...

ORGANISM(S): Mus musculus

2011-06-30 | E-GEOD-19512 | biostudies-arrayexpress

Antibiotics as first-line alternative to appendicectomy in adult appendicitis: 90-day follow-up from a prospective, multicentre cohort study.

Not available

S-EPMC8499866 | biostudies-literature

Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study).

Not available

S-EPMC9071082 | biostudies-literature

Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomised, double-blind, placebo-controlled phase 3 trial.

Not available

S-EPMC9830601 | biostudies-literature

Preliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa.