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UnknownTiming and causes of mid-Holocene mammoth extinction on St. Paul Island, Alaska.
Not available
S-EPMC4995940 | biostudies-literature
TranscriptomicsCharacterisation of the whole blood mRNA transcriptome in Holstein-Friesian and Jersey calves in response to gradual weaning
The objectives of the study were to use RNA-Seq to examine the effect of (i) breed and (ii) gradual weaning, on the whole blood mRNA transcriptome of artificially reared Holstein-Friesian and Jersey calves. The calves were gradually weaned over 14 days (day (d) -13 to d 0) and mRNA transcription was...
ORGANISM(S): Bos taurus 
2016-08-19 | E-GEOD-76841 | biostudies-arrayexpress
ProteomicsCoupling microdroplet-based sample preparation, multiplexed isobaric labeling, and nanoflow peptide fractionation for deep proteome profiling of tissue microenvironment
Existing spatially-resolved proteomics technologies cannot provide deep proteome coverage due to limited sensitivity and poor sample recovery. Herein, we seamlessly combined laser capture microdissection with a low-volume sample processing technology that includes a microfluidic device named microPO...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-01-25 | MSV000093925 | MassIVE
TranscriptomicsGenetic toxicology and toxicogenomic analysis of 3 cigarette smoke condensates in vitro reveals few differences between high and low tar brands
This experiment investigated the response of mouse pulmonary epithelial cells in culture (FE1 cell line) to 3 different brands of cigarette smoke condensate. The three brands represent a full flavour, regular and king-size light cigarettes. These vary in some key chemical consistuents. Brand #1 has ...
ORGANISM(S): Mus musculus 
2012-04-01 | E-GEOD-30079 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of kidney samples from Wilms tumor patients to accurately map 1p13 breakpoints
Wilms tumour karyotypes frequently exhibit recurrent, large-scale chromosomal imbalances, among the most common of which are concurrent loss of 1p and gain of 1q. We have previously identified a novel breakpoint at 1p13 by 1Mb-spaced array CGH, and undertook a fine-tiling oligonucleotide array appro...
ORGANISM(S): Homo sapiens 
2007-03-21 | E-TABM-155 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of kidney samples from Wilms tumor patients to examine down- and up-regulation of genes either side of 1p13 breakpoints
Wilms tumour karyotypes frequently exhibit recurrent, large-scale chromosomal imbalances, among the most common of which are concurrent loss of 1p and gain of 1q. We have previously identified a novel breakpoint at 1p13 by 1Mb-spaced array CGH, and undertook a fine-tiling oligonucleotide array appro...
ORGANISM(S): Homo sapiens 
2007-03-21 | E-TABM-164 | biostudies-arrayexpress
UnknownA pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.
Not available
S-EPMC3561909 | biostudies-literature
UnknownGenetic comorbidities in Parkinson's disease.
Not available
S-EPMC3888265 | biostudies-literature
TranscriptomicsTranscription profiling of acteylcholine receptor immunization between RIIIS/J and B10.RIII mice
Comparison of acetylcholine receptor immunization between RIIIS/J and B10.RIII mice.
ORGANISM(S): Mus musculus 
2004-03-11 | E-MEXP-86 | biostudies-arrayexpress
ProteomicsProteomic profiling of intra-islet features reveals substructure-specific protein signatures
LCM-coupled nanoPOTS proteomics using FAIMS of intra-islet microstructures. 5 acinar samples, 5 whole islets, 5 islet interface vasculature pools, 5 islet inner microvasculature pools, 3 islets after microsvasculature removed.
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2022-01-25 | MSV000088730 | MassIVE
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