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TranscriptomicsExpression data from 30do mouse spermatid [Affymetrix]
Chromatin performs numerous functions during cellular differentiation, and therefore it must be capable of adopting a multitude of different structures. How these various structures are established is poorly understood, but we propose that specific histone H2A variants will have a key role in remode...
ORGANISM(S): Mus musculus 
2012-01-20 | E-GEOD-29781 | biostudies-arrayexpress
TranscriptomicsH2A.Z inheritance during the cell cycle [expression array]
While it has been clearly established that well positioned H2A.Z-containing nucleosomes flank the nucleosome depleted region (NDR) at the transcriptional start site (TSS) of active mammalian genes 1,2, how this chromatin-based information is transmitted through the cell cycle is unknown. We show her...
ORGANISM(S): Mus musculus 
2012-11-23 | E-GEOD-41370 | biostudies-arrayexpress
GenomicsFunctional studies of a H2A.Bbd-like histone variant in mouse spermatogenesis
This SuperSeries is composed of the following subset Series: GSE29781: Expression data from 30do mouse spermatids [Affymetrix] GSE29913: Genome-wide distribution maps of histone variants H2A.Lap1 and H2A.Z in 30do mouse spermatids[ChIP_seq] Refer to individual Series
ORGANISM(S): Mus musculus 
2012-01-20 | E-GEOD-29916 | biostudies-arrayexpress
TranscriptomicsH2A.Z inheritance during the cell cycle
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2012-11-23 | E-GEOD-41091 | biostudies-arrayexpress
TranscriptomicsThe alternative complement pathway appears to be a UVA sensor that leads to systemic immunosuppression
Ultraviolet (UV) wavebands in sunlight are immunomodulatory. About half the amount of UVA within a minimum erythemal dose of sunlight is systemically immunosuppressive, while higher doses protect from UVB immunosuppression in mice. We have previously shown that these responses to UVA are genetically...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-15618 | biostudies-arrayexpress
GenomicsGenome-wide distribution maps of histone variants H2A.Lap1 and H2A.Z in 30do mouse spermatids [ChIP_seq]
Chromatin performs numerous functions during cellular differentiation, and therefore it must be capable of adopting a multitude of different structures. How these various structures are established is poorly understood, but we propose that specific histone H2A variants will have a key role in remode...
ORGANISM(S): Mus musculus 
2012-01-20 | E-GEOD-29913 | biostudies-arrayexpress
MetabolomicsIntegration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance
The development of reliable, mixed-culture biotechnological processes hinges on understanding how microbial ecosystems respond to disturbances. Here we reveal extensive phenotypic plasticity and niche complementarity in oleaginous microbial populations from a biological wastewater treatment plant. W...
2021-04-06 | MTBLS2021 | MetaboLights
GenomicsH2A.Z inheritance during the cell cycle and its impact on promoter organization and dynamics [ChIP-seq]
While it has been clearly established that well positioned H2A.Z-containing nucleosomes flank the nucleosome depleted region (NDR) at the transcriptional start site (TSS) of active mammalian genes, how this chromatin-based information is transmitted through the cell cycle is unknown. We show here th...
ORGANISM(S): Mus musculus 
2012-11-23 | E-GEOD-41371 | biostudies-arrayexpress
TranscriptomicsIntra- and inter-individual genetic differences in gene expression
Each expressed gene was tested for differential expression in three mouse tissues (Brain, Kidney, Liver) in a direct comparison of SJL/J vs. C57BL/6J Keywords: direct comparison, multiple tissues Whole RNA from a pool of 5 SJL/J mice was compared to a pool of RNA from C57BL/6J mice with three techni...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-8358 | biostudies-arrayexpress
TranscriptomicsIntra- and inter-individual genetic differences in gene expression (BXD Brain)
Genetic variation is known to influence the amount of mRNA produced by a gene. Because molecular machines control mRNA levels of multiple genes, we expect genetic variation in components of these machines would influence multiple genes in a similar fashion. We show that this assumption is correct by...
ORGANISM(S): Mus musculus 
2010-06-25 | E-GEOD-8355 | biostudies-arrayexpress
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