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TranscriptomicsExamination of glycan-related gene expression in the livers of three groups of mice: wild-type, ad-lib-fed type 2 diabetic mice (db/db), and calorically restricted db/db mice
Assembly of HSPGs in the liver is defective in diabetes mellitus. A major consequence is impaired clearance of post-prandial lipoproteins, which ordinarily depends on the binding of these particles to hepatic HSPGs. Impaired clearance leads to prolonged exposure of the arterial wall to these harmf...
ORGANISM(S): Mus musculus 
2011-04-29 | E-GEOD-28938 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of male flounder isolated from different rivers
Comparison of environmentally sampled flounder from the Tyne and Alde estuaries, related experiment E-MEXP-15
ORGANISM(S): Platichthys flesus 
2005-01-01 | E-MEXP-14 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of female flounders isolated from different rivers
Comparison of environmentally sampled flounder from the Tyne and Alde estuaries, related experiment, E-MEXP-14
ORGANISM(S): Platichthys flesus 
2006-10-25 | E-MEXP-15 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse murine dorsal neural tube bisected along the midline with one half from each embryo used for control and the other half treated with 10-6M RA dissolved in ethanol for 6, 12, 24 or 48 h
This series represents murine dorsal neural tube bisected along the midline with one half from each embryo used for control and the other half treated with 10-6M RA dissolved in ethanol for 6, 12, 24 or 48 h. For 6 h exposures, the explants were cultured overnight on fibronectin coated 35mm dishes (...
ORGANISM(S): Mus musculus 
2007-10-11 | E-GEOD-1588 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of adenoma and corresponding normal mucosa in human colorectal cancer cases
The differences in gene expression profile between adenoma and corresponding normal mucosa in colorectal cancer cases.
ORGANISM(S): Homo sapiens 
2005-05-20 | E-MEXP-341 | biostudies-arrayexpress
TranscriptomicsMolecular anatomy of gene expression responses in stressed hepatocytes
It is well-known that isolation and cultivation of primary hepatocytes causes major gene expression alterations. In the present genome-wide, time resolved study of cultivated human and mouse hepatocytes, we made the observation that expression changes in culture strongly resemble alterations in live...
ORGANISM(S): Mus musculus 
2016-09-28 | E-MTAB-4444 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat heart response to hypoxia treatment of parental Fawn Hooded Hypertensive (FHH) and consomic Brown Norway (FHH1BN) rat
Examination of gene expression associated with hypoxia treatment of parental Fawn Hooded Hypertensive (FHH) and consomic Brown Norway (FHH1BN) rat strain. FHH1BN rats are derived from introgression of chromosome 1 from BN rats into the FHH genetic background.
ORGANISM(S): Rattus rattus 
2006-01-15 | E-TIGR-24 | biostudies-arrayexpress
TranscriptomicsThe Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS
Apc, a negative regulator of the canonical Wnt signaling pathway, is a bona-fide tumor suppressor whose loss of function results in intestinal polyposis. APC is located in a commonly deleted region on human chromosome 5q, associated with myelodysplastic syndrome (MDS) suggesting that haploinsufficie...
ORGANISM(S): Mus musculus 
2010-02-21 | E-GEOD-20352 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of heart during hypoxia of the Fawn Hooded Hypertensive (FHH) rat and FHH12BN consomic rat
Examination of gene expression changes during hypoxia of the Fawn Hooded Hypertensive (FHH) rat and FHH12BN consomic rat. FHH12BN rats are derived from introgression of chromosome 12 and from the Brown Norway (BN) rat into the FHH genetic background.
ORGANISM(S): Rattus norvegicus 
2006-09-15 | E-TIGR-111 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat lung response to hypoxia treatment of parental salt sensitive (SS) and consomic Brown Norway (SSYBN) rat strain
Examination of gene expression associated with hypoxia treatment of parental salt sensitive (SS) and consomic Brown Norway (SSYBN) rat strain. SSYBN rats are derived from introgression of chromosome Y from BN rats into the SS genetic background.
ORGANISM(S): Rattus rattus 
2005-01-01 | E-TIGR-80 | biostudies-arrayexpress
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