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MetabolomicsIn plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (Imaging MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS769 | MetaboLights
TranscriptomicsTranscription profiling of rat hippocampus treated with kainate to induce seizures - time series
Mesial temporal lobe epilepsy (MTLE) is the most common medically refractory epilepsy syndrome; kainic acid (KA) induced seizures have been studied as a MTLE model as limbic seizures produced by systemic injections of KA result in a distinctive pattern of neurodegeneration in the hippocampus that re...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1834 | biostudies-arrayexpress
ProteomicsPptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
Mitochondrial proteins are replete with phosphorylation; however, the origin, abundance, and functional relevance of these modifications are largely unclear. Nonetheless, mitochondria possess multiple resident phosphatases, suggesting that protein dephosphorylation may be broadly important for mitoc...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-29 | PXD012743 | Pride
Mitochondia Pptc7 Phosphoproteome 
MetabolomicsChanges in lipid profiles of epileptic mouse model

INTRODUCTION: Approximately 1% of the world's population is impacted by epilepsy, a chronic neurological disorder characterized by seizures. One-third of epileptic patients are resistant to AEDs, or have medically refractory epilepsy (MRE). One non-invasive treatment that exists...

2022-01-06 | MTBLS1432 | MetaboLights
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
MetabolomicsPostprandial Metabolism is Impaired in Overweight Normoglycemic Young Adults without Family History of Diabetes

While the risk factors for Type 2 diabetes (T2DM) are known, early predictive markers of transition from normal to a prediabetes state are unidentified. We studied the basal metabolism and metabolic response to a mixed-meal challenge in 110 healthy subjects in the age group of 18 to 40 years (Mal...

2019-03-14 | MTBLS743 | MetaboLights
UnknownModified ion source triple quadrupole mass spectrometer gas chromatograph for polycyclic aromatic hydrocarbon analyses.
Not available
S-EPMC4721517 | biostudies-literature
UnknownYounger Dryas glacier advances in the tropical Andes driven by increased precipitation.
Not available
S-EPMC12370917 | biostudies-literature
MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
UnknownWhole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals.
Not available
S-EPMC12418676 | biostudies-literature
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