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GenomicsThe androgen receptor induces a distinct transcriptional program in castration resistant prostate cancer in man
The androgen receptor (AR) is the major transcriptional driver of prostate cell growth in man. For the first time, we define AR targets in prostate cancer (PC) tissue representing progression from treatment-naive to castrate-resistant disease (CRPC). We employed chromatin immunoprecipitation with hi...
ORGANISM(S): Homo sapiens 
2013-01-04 | E-GEOD-28219 | biostudies-arrayexpress
UnknownGenome Comparisons of Wild Isolates of Caulobacter crescentus Reveal Rates of Inversion and Horizontal Gene Transfer.
Not available
S-EPMC6368467 | biostudies-literature
UnknownThe Results of the Families Improving Together (FIT) for Weight Loss Randomized Trial in Overweight African American Adolescents.
Not available
S-EPMC9528795 | biostudies-literature
UnknownHigher Adherence to a Mediterranean Diet Is Associated with Improved Insulin Sensitivity and Selected Markers of Inflammation in Individuals Who Are Overweight and Obese without Diabetes.
Not available
S-EPMC9608711 | biostudies-literature
GenomicsSynthetic antagonist of a histone reader reveals and targets genes essential for inflammation
Post-translational modifications of histones determines cell lineage- or signal-specific gene expression. Depending on the type and combination of modifications, histones bind to functionally distinct effector proteins ('readers') that control gene activation or silencing. The current pharmacologic...
ORGANISM(S): Mus musculus 
2010-11-10 | E-GEOD-21910 | biostudies-arrayexpress
TranscriptomicsPlatform Comparison Study
Microarray technology is a powerful tool able to measure RNA expression for thousands of genes at once. Various studies have been published comparing competing platforms with mixed results: some find agreement, others do not. As the number of researchers starting to use microarrays and the number of...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-2521 | biostudies-arrayexpress
UnknownDesign innovations and baseline findings in a long-term Parkinson's trial: the National Institute of Neurological Disorders and Stroke Exploratory Trials in Parkinson's Disease Long-Term Study-1.
Not available
S-EPMC3481179 | biostudies-literature
UnknownSialic acid blockade inhibits the metastatic spread of prostate cancer to bone.
Not available
S-EPMC11134892 | biostudies-literature
ProteomicsProteogenomic analysis of chemo-refractory high grade serous ovarian cancer
To improve our understanding of the molecular basis of chemo-refractory high grade serous ovarian cancers (HGSOCs), we characterized the proteogenomic landscape of 242 (refractory and sensitive) HGSOCs, representing one discovery and two independent validation cohorts (spanning four academic centers...
ORGANISM(S): Homo Sapiens 
PXD040742 | panorama
UnknownTargetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.
Not available
S-EPMC4191900 | biostudies-literature
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