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UnknownEmerging Epigenetic Therapeutic Targets in Acute Myeloid Leukemia.
Not available
S-EPMC6743337 | biostudies-literature
UnknownMalignant Phenotypes in Metastatic Melanoma are Governed by SR-BI and its Association with Glycosylation and STAT5 Activation.
Not available
S-EPMC5751895 | biostudies-literature
UnknownDrug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.
Not available
S-EPMC6037300 | biostudies-literature
UnknownSTAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway.
Not available
S-EPMC7116782 | biostudies-literature
UnknownPre-clinical activity of combined LSD1 and mTORC1 inhibition in MLL-translocated acute myeloid leukaemia.
Not available
S-EPMC7192845 | biostudies-literature
UnknownO-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.
Not available
S-EPMC5629373 | biostudies-literature
ProteomicsThe ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
The marsupial Tasmanian devil (Sarcophilus harrisii) faces extinction due to transmissible devil facial tumor disease (DFTD). To unveil the culprit molecular underpinnings, we designed an approach that combines sensitivity to drugs with an integrated systems-biology characterization. Sensitivity to ...
ORGANISM(S): Sarcophilus harrisii 
2019-01-18 | PXD009283 | Pride
Tasmanian devil Dftd Transmissible cancer Erbb 
UnknownHMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block.
Not available
S-EPMC7613766 | biostudies-literature
UnknownPharmacologic inhibition of STAT5 in acute myeloid leukemia.
Not available
S-EPMC5940656 | biostudies-literature
ProteomicsHMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer 1 transcription repression and leukemia cell differentiation block
Pharmacologic inhibition of LSD1 induces molecular and morphologic differentiation of blast cells in acute myeloid leukaemia (AML) patients harboring MLL gene translocations. In addition to its demethylase activity, LSD1 has a critical scaffolding function at genomic sites occupied by the SNAG domai...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD030581 | Pride
Human ltq orbitrap velos 
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