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TranscriptomicsRNA-sequencing of preoptic area leptin receptor-expressing neurons from heat acclimated LepRCreHTB mice
This experiment intended to look for the transcriptome changes that happen in neuronal cells from the preoptic area of the hypothalamus expressing leptin receptors during heat acclimation conditions. 3 groups of animals were used; long-term heat-acclimated animals constantly exposed to 36˚C for 28-3...
ORGANISM(S): Mus musculus 
2024-05-06 | E-MTAB-14029 | biostudies-arrayexpress
TranscriptomicsComparison of Hi-C results using in-solution versus in-nucleus ligation
Chromosome conformation capture (3C) and derivative (4C, 5C and Hi-C) methods employ ligation of diluted cross-linked chromatin complexes, intended to favor proximity-dependent, intra-complex ligation. We previously described an alternative Hi-C protocol with ligation in preserved nuclei rather than...
ORGANISM(S): Mus musculus 
2015-08-12 | E-GEOD-70181 | biostudies-arrayexpress
GenomicsPromoter capture GM12878 CD34
Genome organization influences transcriptional regulation by facilitating interactions between gene promoters and distal regulatory elements. To analyse distal promoter contacts we used Capture Hi-C (CHi-C) to enrich for promoter-interactions in a HiC lib
ORGANISM(S): Homo sapiens 
2015-03-01 | E-MTAB-2323 | biostudies-arrayexpress
GenomicsPromoter capture mESC and fetal liver
Genome organization influences transcriptional regulation by facilitating interactions between gene promoters and distal regulatory elements. To analyse distal promoter contacts we used Capture Hi-C (CHi-C) to enrich for promoter-interactions in HiC libraries from mouse ESC and E14.5 fetal liver. Pl...
ORGANISM(S): Mus musculus 
2015-02-01 | E-MTAB-2414 | biostudies-arrayexpress
TranscriptomicsCHiCAGO: Robust Detection of DNA Looping Interactions in Capture Hi-C data
Capture Hi-C (CHi-C) is a state-of-the art method for profiling chromosomal interactions involving targeted regions of interest (such as gene promoters) globally and at high resolution. Signal detection in CHi-C data involves a number of statistical challenges that are not observed when using other ...
ORGANISM(S): Mus musculus 
2016-05-18 | E-GEOD-81503 | biostudies-arrayexpress
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