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ProteomicsRegulation of the stress proteome by SCD1
Cytotoxic stress activates stress-activated kinases, initiates adaptive mechanisms, including the unfolded protein response (UPR) and autophagy, and induces programmed cell death. Fatty acid unsaturation prevents cytotoxic stress but the mechanisms are diffuse. We investigated changes in the proteom...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-06 | PXD025396 | Pride
Autophagy Erad Phospholipid Programmed cell death Upr Stress signaling Monounsaturated fatty acid Mouse fibroblast 
UnknownDandruff-associated Malassezia genomes reveal convergent and divergent virulence traits shared with plant and human fungal pathogens.
Not available
S-EPMC2141845 | biostudies-literature
TranscriptomicsMicroarray correpsonding to the paper manuscript titled: Targeted expression profiling of single disseminated cancer cells isolated from bone marrow of prostate cancer patients
Bone is the most frequent site of metastasis in prostate cancer (PCa) and patients with bone metastases are deemed incurable. Targeting prostate cancer cells that disseminated to the bone marrow (BM) prior to surgery and before metastatic outgrowth may therefore prevent lethal metastasis. This promp...
ORGANISM(S): Homo sapiens 
2014-10-20 | E-GEOD-59631 | biostudies-arrayexpress
UnknownDistinct chromophore-protein environments enable asymmetric activation of a bacteriophytochrome-activated diguanylate cyclase.
Not available
S-EPMC6956517 | biostudies-literature
ProteomicsProteomic alterations in the context of survival signaling and redox homeostasis linked to de novo fatty acid biosynthesis
Cell death programs like apoptosis, necroptosis, and ferroptosis have an oxidative component linked to lipid metabolism that impacts membrane homeostasis. Evidence for cross-talk between these programs is emerging, highlighting the need for overarching regulatory mechanisms. We investigated changes ...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-04 | PXD053866 | Pride
Programmed cell death Phospholipids Monounsaturated fatty acid Redox homeostasis Mouse fibroblast Cytotoxic stress 
ProteomicsRegulation of stress signaling by SCD1
Cytotoxic stress activates stress-activated kinases, initiates adaptive mechanisms, including the unfolded protein response (UPR) and autophagy, and induces programmed cell death. Fatty acid unsaturation, controlled by stearoyl-CoA desaturase (SCD)1, prevents cytotoxic stress but the mechanisms are ...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-24 | PXD031890 | Pride
Phospholipid Stress signaling Monounsaturated fatty acid Lc-mse Mouse fibroblasts 
UnknownCost-Consequence Analysis of Using Cangrelor in High Angiographic Risk Percutaneous Coronary Intervention Patients: A US Hospital Perspective.
Not available
S-EPMC8748330 | biostudies-literature
TranscriptomicsFungenES: FunGenES_UKOE-4: Functional characterization and transcriptome analysis of embryonic stem cells-derived contractile smooth muscle cells
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the EuropeanUnion, http://www.fungenes.org). The experiment was conducted at University of Cologne, Cologne, Germany. Goal of the experiment is a...
ORGANISM(S): Mus musculus 
2011-02-25 | E-TABM-1123 | biostudies-arrayexpress
UnknownAttenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation.
Not available
S-EPMC11861335 | biostudies-literature
UnknownPI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
Not available
S-EPMC9142606 | biostudies-literature
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