Sort   by:  
 Page size 
MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
TranscriptomicsTranscription analysis of E. coli processed at persistent and decreasing glucose limitation in a fed-batch cultivation
A time series of whole-genome transcription profiling of E. coli K-12 W3110 was performed to study the dynamic physiological response of E. coli K-12 W3110 to limited carbon conditions. cDNA from eight time intervals after glucose limitation, representing different stages of glucose depletion, along...
ORGANISM(S): Escherichia coli W3110 
2010-05-19 | E-GEOD-10307 | biostudies-arrayexpress
TranscriptomicsRNA-seq-based analysis of the physiologic cold shock-induced changes in Moraxella catarrhalis gene expression
Background: Moraxella catarrhalis, a major nasopharyngeal pathogen of the human respiratory tract, is exposed to rapid downshifts of environmental temperature when humans breathe cold air. The prevalence of pharyngeal colonization and respiratory tract infections caused by M. catarrhalis is greatest...
ORGANISM(S): Moraxella catarrhalis O35E 
2013-07-22 | E-GEOD-46256 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and BOLITA over-expressing Arabidopisis leaves
Comparison of BOLITA mutant leaves (gain-of-function mutant) vs. wild type leaves, grown in the same conditions. The BOLITA (BOL) gene (At1g24590), an AP2/ERF transcription factor, was characterized with the help of an activation tag mutant and overexpression lines in Arabidopsis and tobacco. The l...
ORGANISM(S): Arabidopsis thaliana 
2006-08-04 | E-MEXP-809 | biostudies-arrayexpress
ModelsSchilling2009 - ERK distributive
Schilling2009 - ERK distributive This model has been exported from PottersWheel on 2009-04-20 18:57:44.  The PottersWheel Model Definition file can be obtained from the curation tab. This model is described in the article: Theoretical and experimental analysis links ...
2024-09-02 | BIOMD0000000270 | BioModels
UnknownEvaluation of plasma activated liquids for the elimination of mixed species biofilms within endoscopic working channels.
Not available
S-EPMC11576748 | biostudies-literature
TranscriptomicsMeta-transcriptome analysis of a natural wheat sourdough ecosystem during a 10-day spontaneous, laboratory fermentation
Lactic acid bacteria (LAB) are of industrial importance in the production of fermented foods, among which sourdough-derived products. Despite their limited metabolic capacity LAB contribute considerably to important characteristics of fermented foods, among which extended shelf-life, microbial safet...
ORGANISM(S): Lactobacillus pontis 
2010-07-07 | E-GEOD-15693 | biostudies-arrayexpress
TranscriptomicsMeta-transcriptome analysis of a natural wheat sourdough ecosystem during a 10-day spontaneous laboratory fermentation
Lactic acid bacteria (LAB) are of industrial importance in the production of fermented foods, among which sourdough-derived products. Despite their limited metabolic capacity LAB contribute considerably to important characteristics of fermented foods, among which extended shelf-life, microbial safet...
ORGANISM(S): Pediococcus acidilactici 
2010-07-07 | E-GEOD-15686 | biostudies-arrayexpress
TranscriptomicsGenome wide comparison of the inducible transcriptomes of CAR, PXR and PPARα in primary human hepatocytes
To identify the CAR-, PXR- and PPARα-specific genome-wide expression changes, hepatocyte cultures from six individual donors were treated with the prototypical ligands for CAR (CITCO), PXR (rifampicin) and PPARα (WY14,643) as well as DMSO (vehicle control). Afterwards, the mRNA expression in these...
ORGANISM(S): Homo sapiens 
2016-03-24 | E-GEOD-76148 | biostudies-arrayexpress
Sort   by:  
 Page size