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TranscriptomicsIdentification of drought stress related genes in NatA depleted mutants
N-terminal protein acetylation is one of the most common protein modifications in eucaryotes and is catalyzed co-translationally by N-terminal aceytltransferases (Nats). Regarding the number of predictaed substrates, NatA is the main Nat complex in human and yeast and is composed of the catalytic su...
ORGANISM(S): Arabidopsis thaliana 
2015-07-23 | E-GEOD-65414 | biostudies-arrayexpress
TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
TranscriptomicsArabidopsis thaliana ecotype Col-0 versus T-DNA mutant sir1-1
Arabidopsis thaliana Col-0 plants were compared to sir1-1 T-DNA insertion mutants to investigate transcript levels of sulfur metabolism related genes under standard conditions. For wildtype Col-0 and sir1-1, leaf tissue was harvested from 3 independent plants that were 7 weeks old; total RNA was ext...
ORGANISM(S): Arabidopsis thaliana 
2010-05-05 | E-GEOD-20670 | biostudies-arrayexpress
ProteomicsThe proteomic inventory reveals the chloroplast ribosome as nexus within a diverse protein network - Effect of Crosslinking
In plant cells, chloroplast gene expression is predominantly controlled through regulationof translation. Fine-tuning of protein synthesis is vital for plant development, acclimation to environmental challenges and for the assembly of major protein complexes such as the photosynthesis machinery. How...
ORGANISM(S): Chlamydomonas reinhardtii 
2020-11-23 | PXD022210 | Pride
Chlamydomonas Plastide ribosome Ae-ms Lc-ms/ms 
TranscriptomicsExpression data from colon epithelium of STAT3IEC-KO in acute DSS colitis
STAT3 is a pleiotropic transcription factor with important functions in cytokine signalling in a variety of tissues. However, the role of STAT3 in the intestinal epithelium is not well understood. Here we demonstrate that development of colonic inflammation is associated with the induction of STAT3...
ORGANISM(S): Mus musculus 
2009-05-08 | E-GEOD-15955 | biostudies-arrayexpress
ProteomicsMitochondrial alternative NADH dehydrogenases limit ROS, protect chloroplasts and promote survival of reoxygenation in Arabidopsis
Weather extremes are increasing worldwide frequently exposing plants to transient flooding. When floodwaters recede, plants have to cope with increased light intensity and elevated oxygen that favor excessive formation of reactive oxygen species (ROS). We report a novel molecular mechanism that help...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2022-12-02 | PXD032119 | JPOST Repository
ProteomicsKnock out of NAA50 in A. thaliana
Knockout of the N-acetyltransferase AtNAA50 causes severe dwarfism the model plant Arabidopsis thaliana but does not affect the activity of the essential NatA complex.
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2020-05-27 | PXD017663 | JPOST Repository
ProteomicsFast light changes promote distinct responses of plastid protein acetylation marks
Protein acetylation is a key recurring co- and posttranslational modification. How different types of acetylation respond to the same environmental stress is unknown. A member of the newly discovered family of plastid acetyltransferases (GNAT2), which is featuring both lysine- and N-terminal acetyl...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2024-08-19 | PXD040517 | JPOST Repository
ProteomicsThe Nα-acetyltransferase NAA50 mediates plant immunity independent of the NatA complex
Nα-terminal acetylation (NTA) ranges among the most abundant protein modifications in higher eukaryotes. Over 40 % of the human and plant proteome are co-translationally acetylated by a single Nα-acetyltransferase (Nat) termed NatA. The core NatA complex consists of the catalytic subunit NAA10 and t...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2024-03-01 | PXD040755 | JPOST Repository
ProteomicsGlobal profiling of acetylation reveals a new family with dual-specific lysine and N-terminal acetyltransferase activity in the plastids of Arabidopsis
Protein acetylation is a universally conserved modification occurring on N-termini (N--acetylation, NTA) and on internal lysines residues (-lysine-acetylation, KA). So far, NTA and KA were known to be supported by distinct families of enzymes (NATs and KATs, respectively), despite most of them sha...
ORGANISM(S): Escherichia Coli 
2020-07-07 | PXD015875 | JPOST Repository
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