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ProteomicsProteome quantification in WASP wild-type and deficient macrophages using DIA-MS
We knocked out Wiskott-Aldrich Syndrome protein (WASP) in an iPSC line and derived the cells to differentiate into macrophages. We found deficiency of WASP results in overexpression of splicing factors and irregulaly sized nulcear speckles. We performed DIA-MS based quantative proteome analysis for...
ORGANISM(S): Homo sapiens (Human) 
2022-04-21 | PXD033326 | Pride
Human Macrophages Dia-ms 
UnknownWiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Not available
S-EPMC9233711 | biostudies-literature
MetabolomicsCadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes
Obesity is considered as a major public health concern with strong economic and social burdens. Exposure to pollutants such as heavy metals can contribute to the development of obesity and its associated metabolic disorders, including type 2 diabetes and cardiovascular diseases. Adipose tissue is an...
2023-06-29 | MTBLS4128 | MetaboLights
MetabolomicsArsenic induces metabolome remodeling in mature human adipocytes
Human lifetime exposure to arsenic through drinking water, food supply or industrial pollution leads to its accumulation in many organs such as liver, kidneys, lungs or pancreas but also adipose tissue. Recently, population-based studies revealed the association between arsenic exposure and the deve...
2025-05-23 | MTBLS8808 | MetaboLights
UnknownStriatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling.
Not available
S-EPMC5487420 | biostudies-literature
UnknownSPIN90/WISH interacts with PSD-95 and regulates dendritic spinogenesis via an N-WASP-independent mechanism.
Not available
S-EPMC1618117 | biostudies-literature
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