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TranscriptomicsTranscription profiling by array of temporal gene expression in germinating Clostridium difficile 630 endospores
Clostridium difficile is the leading cause of hospital acquired diarrhoea in industrialised countries. Under conditions that are not favourable for growth, the pathogen produces metabolically dormant endospores via asymmetric cell division. These are extremely resistant to both chemical and physical...
ORGANISM(S): Clostridium difficile 
2013-03-16 | E-BUGS-145 | biostudies-arrayexpress
TranscriptomicsProteomic view of the Plasmodium falciparum life cycle
The completion of the Plasmodium falciparum clone 3D7 genome provides a basis on which to conduct comparative proteomics studies of this human pathogen. Here, we applied a high-throughput proteomics approach to identify new potential drug and vaccine targets and to better understand the biology of t...
ORGANISM(S): Plasmodium falciparum 3D7 
2002-12-22 | E-GEOD-92 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Mycobacterium smegmatis response to nitrogen stress using bipartite active modules
BACKGROUND: The ability to adapt to environments with fluctuating nutrient availability is vital for bacterial survival. Although essential for growth, few nitrogen metabolism genes have been identified or fully characterised in mycobacteria and nitrogen stress survival mechanisms are unknown. RESUL...
ORGANISM(S): Mycobacterium smegmatis 
2013-06-10 | E-BUGS-140 | biostudies-arrayexpress
TranscriptomicsThe distribution of mobile genetic elements (MGEs) in MRSA CC398 is associated with both host and country.
Methicillin-resistant Staphylococcus aureus clonal complex (CC) 398 has emerged from pigs to cause human infections in Europe and North America. We used a new 62-strain S. aureus microarray (SAM-62) to compare genomes of isolates from three geographical areas (Belgium, Denmark, and Netherlands) to u...
ORGANISM(S): Staphylococcus aureus 
2012-01-21 | E-BUGS-120 | biostudies-arrayexpress
TranscriptomicsGenetic Variation in Spatio-Temporal Confined USA300 Community-Associated MRSA Isolates: A Shift from Clonal Dispersion to Genetic Evolution?
Introduction Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are increasingly isolated, with USA300-0114 being the predominant clone in the USA. Comparative whole genome sequencing of USA300 isolates collected in 2002, 2003 and 2005 showed a limited number of single nucleo...
ORGANISM(S): Staphylococcus aureus 
2011-04-15 | E-BUGS-108 | biostudies-arrayexpress
UnknownRurality and relative poverty drive acquisition of a stable and diverse gut microbiome in early childhood in a non-industrialized setting.
Not available
S-EPMC11830098 | biostudies-literature
UnknownGenetic variation in Mycobacterium tuberculosis isolates from a London outbreak associated with isoniazid resistance.
Not available
S-EPMC4988016 | biostudies-literature
UnknownUse of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial.
Not available
S-EPMC5371199 | biostudies-literature
UnknownStaphylococcus aureus temperate bacteriophage: carriage and horizontal gene transfer is lineage associated.
Not available
S-EPMC3417521 | biostudies-literature
UnknownMetagenomic profiling of placental tissue suggests DNA virus infection of the placenta is rare.
Not available
S-EPMC8742990 | biostudies-literature
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