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UnknownM3RNA Drives Targeted Gene Delivery in Acute Myocardial Infarction.
Not available
S-EPMC6352545 | biostudies-literature
TranscriptomicsGeminin knockdown in embryonic stem cell-derived neural precursors
Regulating the transition from lineage-restricted progenitors to terminally differentiated cells is a central aspect of nervous system development. Here, we investigated the role of the nucleoprotein Geminin in regulating neurogenesis at a mechanistic level during both Xenopus primary neurogenesis a...
ORGANISM(S): Mus musculus 
2012-12-06 | E-GEOD-39657 | biostudies-arrayexpress
TranscriptomicsSpinal Ependymoma Gene Expression Data
Purpose: Myxopapillary ependymoma (MPE) is a distinct histological variant of ependymoma arising commonly in the spinal cord. Despite an overall favorable prognosis, distant metastases, subarachnoid dissemination, and late recurrences have been reported. Currently the only effective treatment for M...
ORGANISM(S): Homo sapiens 
2015-09-02 | E-GEOD-66787 | biostudies-arrayexpress
TranscriptomicsRAvs.ND
Rheumatoid arthritis (RA) is a chronic, inflammatory joint disease of unknown etiology and pronounced inter-patient heterogeneity. To characterize RA at the molecular level and to uncover key pathomechanisms, we performed whole-genome gene expression analyses. Synovial tissues from rheumatoid arthri...
ORGANISM(S): Homo sapiens 
2004-12-10 | E-GEOD-2053 | biostudies-arrayexpress
TranscriptomicsIntrinsic glioma subtypes in EORTC 26951 (part 6)
Background: Intrinsic glioma subtypes (IGS) are molecularly similar tumors that can be identified based on unsupervised gene-expression analysis. Here, we have evaluated the clinical relevance of these subtypes within EORTC26951, a randomized phase III clinical trial investigating adjuvant procarbaz...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-43353 | biostudies-arrayexpress
UnknownMesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis.
Not available
S-EPMC4498067 | biostudies-literature
TranscriptomicsMYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
MYCN is a master regulator controlling many processes necessary for tumor cell survival. Here, we unravel a microRNA network that causes tumor suppressive effects in MYCN-amplified neuroblastoma cells. In profiling studies, histone deacetylase (HDAC) inhibitor treatment most strongly induced miR-183...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-44538 | biostudies-arrayexpress
Unknown20 Hz beta stimulation of the subthalamic nucleus improves response inhibition in Parkinson's disease.
Not available
S-EPMC12690201 | biostudies-literature
UnknownThe dual role of Andean topography in primary divergence: functional and neutral variation among populations of the hummingbird, Metallura tyrianthina.
Not available
S-EPMC4724075 | biostudies-literature
UnknownPreclinical activity of EGFR and MEK1/2 inhibitors in the treatment of biliary tract carcinoma.
Not available
S-EPMC5239557 | biostudies-literature
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