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TranscriptomicsGene Profiling in the Livers of Wild-Type and PPARalpha-Null Mice Exposed to Perfluorooctanoic Acid (PFOA)
Unlike the PPARalpha agonist W14,643, PFOA is capable of inducing effects independently of PPARa. Genes altered in the PPARalpha-null mouse following exposure to PFOA included those associated with fatty acid metabolism, inflammation, xenobiotic metabolism, and cell cycle progression. The specific s...
ORGANISM(S): Mus musculus 
2008-05-22 | E-GEOD-9796 | biostudies-arrayexpress
UnknownStructural basis of Fanconi anemia pathway activation by FANCM.
Not available
S-EPMC12263834 | biostudies-literature
TranscriptomicsSubtypes of HPV-positive head and neck cancers are associated with HPV characteristics, copy number variations, PIK3CA mutation, and pathway signatures. [RNA-Seq]
Purpose: There is substantial heterogeneity within the human papillomavirus (HPV) positive head and neck cancer (HNC) tumors that predispose them to different outcomes, however this subgroup is poorly characterized due to various historical reasons. Experimental Design: we perform unsupervised gene...
ORGANISM(S): Homo sapiens 
2016-05-13 | E-GEOD-74927 | biostudies-arrayexpress
UnknownProof-of-Concept and Randomized, Placebo-Controlled Trials of an Fcrn Inhibitor, Batoclimab, for Thyroid Eye Disease.
Not available
S-EPMC10655547 | biostudies-literature
UnknownHigh-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008.
Not available
S-EPMC6209090 | biostudies-literature
UnknownCrucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons.
Not available
S-EPMC10197517 | biostudies-literature
UnknownEnabling FAIR data stewardship in complex international multi-site studies: Data Operations for the Accelerating Medicines Partnership® Schizophrenia Program.
Not available
S-EPMC11968805 | biostudies-literature
UnknownSample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program.
Not available
S-EPMC11968923 | biostudies-literature
UnknownIndividualized Atrophy-Based Prediction of Dementia Progression in Familial Frontotemporal Lobar Degeneration With Bayesian Linear Mixed-Effects Modeling.
Not available
S-EPMC12950279 | biostudies-literature
UnknownCollecting language, speech acoustics, and facial expression to predict psychosis and other clinical outcomes: strategies from the AMP® SCZ initiative.
Not available
S-EPMC12528486 | biostudies-literature
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