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TranscriptomicsGenome-wide array comparative genomic hybridization (aCGH) profiling of copy number variations (CNVs) in various dog breeds in comparison to a reference sample
This study used the NimbleGen dog whole genome CGH 2.1M tiling array to assay copy number variants in the dog genome in multiple breeds and wolf. 53 samples of genomic DNA were hybridized to a reference sample. The dataset comprises 2 samples from each of 15 dog breeds, 10 samples from each of 2 dog...
ORGANISM(S): Canis lupus familiaris 
2012-08-21 | E-GEOD-40210 | biostudies-arrayexpress
ProteomicsUnique Histone Proteoforms by Differential Top Down MS
H3.1 and H3.3 quadrupole isolated and fragmented by ETD and EThcD on an Orbitrap Fusion Lumos. Comparison of two cell lines.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-07-14 | MSV000079191 | MassIVE
MetabolomicsLeptin increases hepatic triglyceride export via a vagal mechanism in humans
Recombinant human leptin (metreleptin) reduces hepatic lipid content in patients with lipodystrophy and overweight patients with non-alcoholic fatty liver disease and relative hypoleptinemia independent of its anorexic action. In rodents, leptin signaling in the brain increases very-low-density lipo...
2023-06-07 | MTBLS4231 | MetaboLights
TranscriptomicsS. pombe oxidative stress response time course
S. pombe cells were challenged with 0.5 mM hydrogen peroxide for various periods of time (0, 10, 30, 60, 120, 180 minutes). Total RNA was isolated at each time point, labeled with Cy3 and hybridized on cDNA microarrays competitively with Cy5 labeled RNA pooled from all 6 samples. A biological replic...
ORGANISM(S): Schizosaccharomyces pombe 
2012-02-22 | E-MTAB-891 | biostudies-arrayexpress
TranscriptomicsGlucocorticoid induced gene-regulation in murine bone marrow derived monocytes.
Glucocorticoids (GC) are used as first line therapies for generalized suppression of inflammation (e.g. allergies or autoimmune diseases), but their long-term use is limited by severe side effects. Our previous work has revealed that GC induced a stable anti-inflammatory phenotype in monocytes, the ...
ORGANISM(S): Mus musculus 
2014-09-02 | E-GEOD-54778 | biostudies-arrayexpress
MetabolomicsMetabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli
Priming and activating immune stimuli have profound effects on macrophages, however, studies generally evaluate stimuli in isolation rather than in combination. In this study we have investigated the effects of pro-inflammatory and anti-inflammatory stimuli either alone or in combination on macropha...
2018-03-13 | MTBLS570 | MetaboLights
UnknownDecreased prevalence rate of respiratory pathogens in hospitalized patients during the COVID-19 pandemic: possible role for public health containment measures?
Not available
S-EPMC7833997 | biostudies-literature
UnknownSystematic review on effects of experimental orthodontic tooth displacement on brain activation assessed by fMRI.
Not available
S-EPMC10982672 | biostudies-literature
UnknownInsights into archaeal evolution and symbiosis from the genomes of a nanoarchaeon and its inferred crenarchaeal host from Obsidian Pool, Yellowstone National Park.
Not available
S-EPMC3655853 | biostudies-literature
UnknownPlasma Metabolite Signature Classifies Male LRRK2 Parkinson's Disease Patients.
Not available
S-EPMC8876175 | biostudies-literature
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