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Transcriptomics40 IPF patients and 8 healthy controls
There is microscopic spatial and temporal heterogeneity of pathologic changes in idiopathic pulmonary fibrosis (IPF) lung tissue, which may relate to heterogeneity in pathophysiological mediators of disease and clinical progression. We measured gene expression in samples from lung biopsies or explan...
ORGANISM(S): Homo sapiens 
2014-10-14 | E-GEOD-53845 | biostudies-arrayexpress
TranscriptomicsHuman bronchial epithelial cells_Passage 3 vs. passage 0
Squamous metaplasia is common in smokers and is associated with airway obstruction in chronic obstructive pulmonary disease (COPD). A major mechanism of airway obstruction in COPD is thickening of the small airway walls. We asked whether squamous metaplasia actively contributes to airway wall thicke...
ORGANISM(S): Homo sapiens 
2007-08-30 | E-GEOD-7557 | biostudies-arrayexpress
TranscriptomicsDrop-seq analysis of bleomycin-treated and control mouse lung single-cell suspensions
Cell suspensions were prepared from mouse lungs dissociated at baseline or 14 days after intratracheal bleomycin injury, and single cell mRNA-seq libraries were generated with Drop-seq.
ORGANISM(S): Mus musculus 
2018-10-25 | E-MTAB-7142 | biostudies-arrayexpress
UnknownSelumetinib in children with neurofibromatosis type 1 and asymptomatic inoperable plexiform neurofibroma at risk for developing tumor-related morbidity.
Not available
S-EPMC9629448 | biostudies-literature
ProteomicsMarkers of neutrophil degranulation in the lung microenvironment linked to idiopathic pulmonary fibrosis severity and survival
Idiopathic pulmonary fibrosis (IPF) leads to progressive loss of lung function and mortality. Understanding mechanisms and markers of lung injury in IPF is paramount to improving outcomes for these patients. Despite the lack of systemic involvement in IPF, many analyses focus on identifying circulat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-05-29 | MSV000098032 | MassIVE
UnknownSelumetinib in Children with Inoperable Plexiform Neurofibromas.
Not available
S-EPMC7305659 | biostudies-literature
UnknownSirolimus Use in Liver Transplant Recipients With Hepatocellular Carcinoma: A Randomized, Multicenter, Open-Label Phase 3 Trial.
Not available
S-EPMC4683033 | biostudies-literature
TranscriptomicsIPF AEx Series
Viruses in acute exacerbations of idiopathic pulmonary fibrosis Keywords: viral detection BAL from patients with acute exacerbations of IPF and stable IPF were hybridized to a pan-viral cDNA microarray to evaluate the presence of virus during these episodes
ORGANISM(S): Viruses 
2011-03-03 | E-GEOD-27578 | biostudies-arrayexpress
UnknownCough-Specific Quality of Life Predicts Disease Progression Among Patients With Interstitial Lung Disease: Data From the Pulmonary Fibrosis Foundation Patient Registry.
Not available
S-EPMC9808640 | biostudies-literature
UnknownA prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma.
Not available
S-EPMC2889889 | biostudies-literature
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