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TranscriptomicsExpression data from Mst knockout embryoid bodies and wild type embryoid bodies
Mst1/Mst2 are central components of Hippo pathway. We examined the role of Mst1/Mst2 in ES cell differentiation. In this data set, we include expression data from day 4 and day 8 Mst1/Mst2 knockout ES cell formed embryoid bodies and wild type embryoid body controls. total 4 samples.
ORGANISM(S): Mus musculus 
2014-01-02 | E-GEOD-50219 | biostudies-arrayexpress
ProteomicsProteomic characterization and comparison of the infective and adult life stage secretomes from Necator Americanus and Ancylostoma ceylanicum
Parasitic infections with the hookworms Ancylostoma ceylanicum and Necator americanus are a significant global health burden and current hookworm infection management approaches are limited by modest drug efficacy, costs, risk of reinfection and drug resistance. Subunit vaccines based on proteins ex...
ORGANISM(S): Ancylostoma ceylanicum Necator americanus 
2024-12-19 | PXD049200 | Pride
Ancylostoma ceylanicum L3 Adult Secretome Necator americanus 
TranscriptomicsGraded Nodal/Activin Signaling Governs ES Cell Fate Decisions via Differential Recruitment of Phospho-Smad2 to Oct4 and Distinct Target Gene Subsets
Nodal and Activin are morphogens of the TGFbeta superfamily of signaling molecules that direct differential cell fate decisions in a dose- and distance-dependent manner. During early embryonic development the Nodal/Activin pathway is responsible for the specification of mesoderm, endoderm, node and ...
ORGANISM(S): Mus musculus 
2011-06-30 | E-GEOD-23239 | biostudies-arrayexpress
UnknownDifferential roles for cryptochromes in the mammalian retinal clock.
Not available
S-EPMC6071063 | biostudies-literature
GenomicsMapping of transcription factor binding sites in mouse embryonic stem cells
Transcription factors and their specific interactions with targets are crucial in specifying gene expression programs. To gain insights into the transcriptional regulatory networks in embryonic stem cells, we use chromatin immunoprecipitation coupled to ultra-high-throughput DNA sequencing (ChIP-seq...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-11431 | biostudies-arrayexpress
ProteomicsSilveira_CYP26B1_BioID_P124_6600
Dataset description This dataset consists of 8 raw MS files and associated peak lists and results files, acquired on AB Sciex TripleTOF 6600 mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by Ema Dreseris. BioID and Mass spectrometry acquisition was performed ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-26 | MSV000091800 | MassIVE
TranscriptomicsGlobal gene expression profiles in Oct4-knockdown and Ccna2-knockdown mouse embryos.
Gene regulation at the maternal-embryonic transition in the pre-implantation mouse embryo is not well understood. We knock down Ccna2 to establish proof-of-concept that antisense morpholino oligonucleotides can be used to target specific genes. We applied this strategy to study Oct4 and discovered...
ORGANISM(S): Mus musculus 
2008-12-30 | E-GEOD-13981 | biostudies-arrayexpress
TranscriptomicsHypoxia-induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling
Hypoxia (low oxygen) and Notch signaling are two important regulators of vascular development, but how they interact in controlling the choice between arterial and venous fates for endothelial cells during vasculogenesis is less well understood. In this report, we show that hypoxia and Notch signali...
ORGANISM(S): Mus musculus 
2013-02-08 | E-GEOD-35894 | biostudies-arrayexpress
UnknownProteomic characterization and comparison of the infective and adult life stage secretomes from Necator americanus and Ancylostoma ceylanicum.
Not available
S-EPMC11745416 | biostudies-literature
UnknownClinical phenotypes and outcomes in children with multisystem inflammatory syndrome across SARS-CoV-2 variant eras: a multinational study from the 4CE consortium.
Not available
S-EPMC10511777 | biostudies-literature
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