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TranscriptomicsFunctional Evidence Implicating Chromosome 7q22 Haploinsufficiency in Myelodysplastic Syndrome Pathogenesis
Purpose: 5A3+/del mice, which have a heterozygous germ line deletion of a 2-Mb interval of chromosome band 5A3 syntenic to a commonly deleted segment of human 7q22, exhibit hematopoietic stem cell (HSC) abnormalities that may contribute to myelodysplastic syndrome (MDS) pathogenesis. These defects a...
ORGANISM(S): Mus musculus 
2015-09-09 | E-GEOD-72811 | biostudies-arrayexpress
ProteomicsMining Yeast Diversity Unveils Novel Targets for Improved Heterologous Laccase Production in Saccharomyces cerevisiae
Analysis of proteins from total cell lysates of 21 different Saccharomyces cerevisiae strains while expressing Trametes trogii laccase.
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
MSV000095757 | MassIVE
UnknownMulti-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.
Not available
S-EPMC12330429 | biostudies-literature
UnknownGenetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Not available
S-EPMC10937372 | biostudies-literature
UnknownMulti-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.
Not available
S-EPMC10081410 | biostudies-literature
UnknownMulti-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Not available
S-EPMC9179018 | biostudies-literature
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