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TranscriptomicsExpression profile for BW25113 M-NM-^TmqsRA with deoxycholate stress
MqsR/MqsA is a well-characterized toxin/antitoxin system with several regulatory roles. Deletion of mqsRA reduced growth with deoxycholate stress. Here we performed a microarray to determine the expression profile with and without mqsRA under deoxycholate stress to determine transcriptional regulat...
ORGANISM(S): Escherichia coli BW25113 
2015-01-09 | E-GEOD-59441 | biostudies-arrayexpress
TranscriptomicsWhole transcriptome sequencing reveals dynamic RNA changes in the aging rat brain
Using RNA-seq, 9 cerebral cortex RNA samples were sequenced from 6 month (n=3, 6 individuals pooled), 12 month (n=3, 6 individuals pooled) and 28 month (n=3, 6 individuals pooled) rats. Allowing brain aging in the cerebral cortex to be assessed. Transcriptional profiling of the ageing cerebral corte...
ORGANISM(S): Rattus norvegicus 
2012-05-09 | E-GEOD-34272 | biostudies-arrayexpress
no omics definedHigh throughput sequenceing of fission yeast to survey the dynamic repertoire of a eukaryotic transcriptome at the single nucleotide resolution
Recent data from several organisms indicate that the transcribed portions of genomes are larger and more complex than expected, and many functional properties of transcripts are not based on coding sequences but on regulatory sequences in untranslated regions or non-coding RNAs. Alternative start a...
ORGANISM(S): Schizosaccharomyces pombe 
2008-12-10 | E-MTAB-5 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of hypothalamic leucine-sensing neurons via PhosphoTRAP
To identify the molecular signature of leucine-activated neurons in the MBH, we adopted the PhosphoTRAP assay following parenchymal injection of leucine into the MBH. Neurons activated following MBH leucine injection (and expressing the neuronal activation marker cFos) co-express Ser240/244-phospho...
ORGANISM(S): Mus musculus 
2026-04-01 | E-MTAB-16665 | biostudies-arrayexpress
UnknownRandomized Phase III Trial of Adjuvant Pazopanib Versus Placebo After Nephrectomy in Patients With Localized or Locally Advanced Renal Cell Carcinoma.
Not available
S-EPMC6018511 | biostudies-literature
TranscriptomicsPrimary Central Nervous System Lymphomas. A validation study of array-based Comparative Genomic Hybridization in Formalin-Fixed Paraffin-Embedded Tumor Specimens
Purpose: Only a limited number of genetic studies have been performed in primary central nervous system lymphomas (PCNSL), partly due to the rarity of the tumors and the very limited amount of available tissue. In this report, we present the first molecular characterization of copy-number abnormali...
ORGANISM(S): Homo sapiens 
2012-04-29 | E-GEOD-28952 | biostudies-arrayexpress
TranscriptomicsExpression profile for overproduction of DosP
Persister cells are a sub-population of all bacterial cultures which exhibit a non-inheritable, multi-drug tolerance when subjected to lethal antibiotic challenge. These persisters arise as a result of metabolic dormancy, and can resume growth subsequent to antibiotic challenge, leading to recalcit...
ORGANISM(S): Escherichia coli K-12 
2014-09-15 | E-GEOD-47427 | biostudies-arrayexpress
TranscriptomicsExpression profile for PA14 lasR rhlR double mutant with H2O2 stress
Quorum sensing controls the expression of multiple virulence factors. PA14 genes lasR and rhlR are necessary for quorum sensing via homoserine lactones. A PA14 lasR rhlR deficient mutant exhibits a reduced oxidative stress response. Here we conducted a microarray to determine oxidative stress resp...
ORGANISM(S): Pseudomonas aeruginosa 
2015-01-09 | E-GEOD-54245 | biostudies-arrayexpress
GenomicsP300 ChIP-Seq analysis of PC3 cells treated with MnTE-2-PyP or not 24 hours prior to irradiation of 20 Gy.
In order to identify how MnTE-2-PyP affects p300 association to chromatin genome-wide, we performed a p300 chromatin Immunoprecipitation assay followed by Next Generation Sequencing on PC3 cells treated with or without MnTE-2-PyP one hour post-irradiation (Figure 3A). Based on the called peaks near ...
ORGANISM(S): Homo sapiens 
2015-10-27 | E-GEOD-74351 | biostudies-arrayexpress
TranscriptomicsExpression profile for overproduction of ArT
Toxin-antitoxin (TA) systems are ubiquitous throughout bacterial and archaeal genomes. TA systems consist of a stable toxin that inhibits growth and a labile antitoxin that prevents toxicity of the toxin. Here we made an artificial TA system (arT/arA) and performed a DNA microarray study for overpr...
ORGANISM(S): Escherichia coli BW25113 
2014-05-13 | E-GEOD-54271 | biostudies-arrayexpress
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