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TranscriptomicsAmitriptyline-mediated cognitive enhancement in aged 3xTg Alzheimer’s disease mice is associated with neurogenesis and neurotrophic activity
Approximately 35 million people worldwide suffer from Alzheimer’s disease (AD). Existing therapeutics, while moderately effective, are currently unable to stem the widespread rise in AD prevalence. AD is associated with an increase in amyloid beta (A) oligomers and hyperphosphorylated tau, along wit...
ORGANISM(S): Mus musculus 
2011-12-31 | E-GEOD-26836 | biostudies-arrayexpress
UnknownMorphological and molecular analyses reveal two new insular species of Cnemaspis Strauch, 1887 (Squamata, Gekkonidae) from Satun Province, southern Thailand.
Not available
S-EPMC6614150 | biostudies-literature
UnknownHidden diversity of rock geckos within the Cnemaspissiamensis species group (Gekkonidae, Squamata): genetic and morphological data from southern Thailand reveal two new insular species and verify the phylogenetic affinities of C.chanardi and C.kamolnorranathi.
Not available
S-EPMC9836533 | biostudies-literature
UnknownJob Strain and the Cortisol Diurnal Cycle in MESA: Accounting for Between- and Within-Day Variability.
Not available
S-EPMC4772437 | biostudies-literature
UnknownMicroRNAs in serum and tissue can differentiate splenic hemangiosarcoma from other splenic masses in dogs.
Not available
S-EPMC12314205 | biostudies-literature
GenomicsNatural variation of histone modification and its impact on gene expression in rat
Histone modifications are epigenetic marks that play fundamental roles in many biological processes including the control of chromatin-mediated regulation of gene expression. To begin to understand the impact of natural variation on histone methylation levels we generated and quantified large-scale ...
ORGANISM(S): Rattus norvegicus 
2012-05-30 | E-MTAB-1102 | biostudies-arrayexpress
UnknownTruncating Variants in <i>RFC1</i> in Cerebellar Ataxia, Neuropathy, and Vestibular Areflexia Syndrome.
Not available
S-EPMC9931080 | biostudies-literature
UnknownImplementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic: an efficient cluster randomised controlled trial using the OpenSAFELY platform.
Not available
S-EPMC10694966 | biostudies-literature
TranscriptomicsA gene regulatory network for neural induction
During early vertebrate development, signals from a special region of the embryo, the organizer, can re-direct the fate of non-neural ectoderm cells to form a complete, patterned nervous system. The process has generally been imagined as the result of a single signaling event, causing a simple switc...
ORGANISM(S): Gallus gallus 
2023-03-14 | E-MTAB-10408 | biostudies-arrayexpress
UnknownSystemic immune challenge exacerbates neurodegeneration in a model of neurological lysosomal disease
Not available
S-SCDT-10_1038-S44321-024-00092-4 | biostudies-other
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