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TranscriptomicsCREB ChIP-chip and HaloCHIP-chip experiments
Regulation of gene expression is essential for normal development and cellular growth. Transcriptional events are tightly controlled both spatially and temporally by specific DNA-protein interactions. In this study we finely map the genome-wide targets of the CREB protein across all known and predi...
ORGANISM(S): Homo sapiens 
2010-05-22 | E-GEOD-18347 | biostudies-arrayexpress
TranscriptomicsDynamic mRNA Expression analysis of cells undergoing synchronous life-cycle differentiation in Trypanosoma brucei
mRNA expression profiles of trypanosomes from two discrete bloodstream form stages of the parasite (slender and stumpy forms), as well as during the transition of the stumpy population to the procyclic life-cycle stage were studied. Our analysis represents the first comparison of in vivo derived ple...
ORGANISM(S): Trypanosoma brucei 
2010-05-16 | E-GEOD-17026 | biostudies-arrayexpress
UnknownSodium channels Na<sub>v</sub>1.7, Na<sub>v</sub>1.8 and pain; two distinct mechanisms for Na<sub>v</sub>1.7 null analgesia.
Not available
S-EPMC11570969 | biostudies-literature
TranscriptomicsWnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells.
We have previously shown that Wnt5A drives invasion in melanoma. We have also shown that Wnt5A promotes resistance to therapy designed to target the BRAF(V600E) mutation in melanoma. Here, we show that melanomas characterized by high levels of Wnt5A respond to therapeutic stress by increasing p21 an...
ORGANISM(S): Homo sapiens 
2015-08-07 | E-GEOD-50004 | biostudies-arrayexpress
UnknownWhole-genome sequencing reveals clinically relevant insights into the aetiology of familial breast cancers.
Not available
S-EPMC6637375 | biostudies-literature
UnknownNatural disturbance impacts on trade-offs and co-benefits of forest biodiversity and carbon.
Not available
S-EPMC8527197 | biostudies-literature
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownEthnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from the RECOVER Initiative.
Not available
S-EPMC11753962 | biostudies-literature
UnknownEffects of empagliflozin on quality of life and healthcare use and costs in chronic kidney disease: a health economic analysis of the EMPA-KIDNEY trial.
Not available
S-EPMC12274867 | biostudies-literature
UnknownGenetic landscape of congenital insensitivity to pain and hereditary sensory and autonomic neuropathies.
Not available
S-EPMC10689924 | biostudies-literature
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