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MYCN is a master regulator controlling many processes necessary for tumor cell survival. Here, we unravel a microRNA network that causes tumor suppressive effects in MYCN-amplified neuroblastoma cells. In profiling studies, histone deacetylase (HDAC) inhibitor treatment most strongly induced miR-183...
ORGANISM(S): Homo sapiens 
MicroRNAs (miRNAs) have been implicated in regulating multiple processes during brain development in various species. However, the function of miRNAs in human brain development remains largely unexplored. Here, we provide a comprehensive analysis of miRNA expression of regionalized neural progenitor...
ORGANISM(S): Homo sapiens 
Extracellular vesicles (EVs) are implicated in the pathogenesis of neurodegenerative diseases and offer a source of biomarkers for diagnostic, stratification and therapeutic monitoring purposes. A major limitation in the development of specific biomarkers based on cerebrospinal fluid (CSF) EVs is t...
ORGANISM(S): Homo sapiens (Human) 
2018-11-30 | PXD006353 | Pride
(paper abstract) Wood is a renewable resource that serves as a sustainable raw material for energy, fuels and materials. A basic understanding of the cambial meristem and the origin of wood cells is critical for forest tree molecular breeding to increase the availability of woody raw materials. Gene...
ORGANISM(S): Populus trichocarpa x Populus deltoides 
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