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ProteomicsCatechol-O-Methyltransferase connects dopamine homeostasis to redox signaling, metal homeostasis and protein folding in schizophrenia
Dysregulation of dopamine (DA) signaling and redox homeostasis contributes to multiple neuropsychiatric and neurodegenerative disorders. Polymorphisms that influence the activity of catechol‑O‑methyltransferase (COMT), an enzyme critical for degrading dopamine (DA) in the dorsolateral prefrontal cor...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-28 | PXD075030 | Pride
Limited proteolysis Thermo-fisher ascend Rat Pc12 cells 
UnknownResuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials.
Not available
S-EPMC2727641 | biostudies-literature
TranscriptomicsPseudomonas aeruginosa PA14 exposed to gliotoxin versus solvent control
Pseudomonas aeruginosa PA14 was precultured in SCFM2, and the OD600 was adjusted to 0.05 in 8 ml of SCFM2, in 6-well flat bottom cell culture plates. Gliotoxin (20 µM) or MeOH (solvent control) was added at log phase (optical density at 600 nm [OD600] = 0.3), and the cultures were incubated statical...
ORGANISM(S): Pseudomonas aeruginosa UCBPP-PA14 
2023-03-30 | E-MTAB-12785 | biostudies-arrayexpress
no omics definedHigh throughput sequenceing of fission yeast to survey the dynamic repertoire of a eukaryotic transcriptome at the single nucleotide resolution
Recent data from several organisms indicate that the transcribed portions of genomes are larger and more complex than expected, and many functional properties of transcripts are not based on coding sequences but on regulatory sequences in untranslated regions or non-coding RNAs. Alternative start a...
ORGANISM(S): Schizosaccharomyces pombe 
2008-12-10 | E-MTAB-5 | biostudies-arrayexpress
UnknownData resource profile: the Edinburgh Child Protection Dataset - a new linked administrative data source of children referred to Child Protection paediatric services in Edinburgh, Scotland.
Not available
S-EPMC10900286 | biostudies-literature
GenomicResearch Program on Genes, Environment and Health (RPGEH)

The Kaiser Permanente Research Program on Genes, Environment, and Health (RPGEH) is a resource developed to facilitate research on genetic and environmental factors on common diseases and healthy aging. The RPGEH resource links biospecimens, health surveys, and comprehensive electronic medical re...

phs000788 | dbGaP
UnknownImpact of Initial CSF Findings on Outcome Among Patients With National Cancer Institute Standard- and High-Risk B-Cell Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group.
Not available
S-EPMC5536164 | biostudies-literature
UnknownImproved Survival for Children and Young Adults With T-Lineage Acute Lymphoblastic Leukemia: Results From the Children's Oncology Group AALL0434 Methotrexate Randomization.
Not available
S-EPMC6366301 | biostudies-literature
TranscriptomicsTranscriptome of the maturing erythroblast
Understanding the pattern of gene expression and identifying the specific genes expressed during erythropoiesis is crucial for a synthesis of erythroid developmental biology. Here we have isolated four distinct populations of erythroblasts at successive erythropoietin-dependent stages of erythropoie...
ORGANISM(S): Homo sapiens 
2011-03-02 | E-GEOD-22552 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression of Arabidopsis in response to fumonisin B1 and exogenous ATP treatments
To identify genes underpinning the antagonistic effects of extracellular ATP on programmed cell death induced by fumonisin B1 (FB1), we conducted a kinetic DNA microarray experiment using samples harvested in the critical time window when exogenous ATP is known to suppress cell death. Arabidopsis ce...
ORGANISM(S): Arabidopsis thaliana 
2019-12-31 | E-MTAB-3685 | biostudies-arrayexpress
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